Stereotactic radiosurgery for chordoma: a report from the North American Gamma Knife Consortium.

Background: Although considered slow-growing, low-grade malignancies, chordomas are locally aggressive and destructive tumors with high recurrence rates.

Objective: To assess patient survival, tumor control, complications, and selected variables that predict outcome in patients who underwent Gamma Knife stereotactic radiosurgery (SRS) as primary, adjuvant, or salvage management for chordomas of the skull base.

Methods: Six participating centers of the North American Gamma Knife Consortium identified 71 patients who underwent SRS for chordoma.