Publications by authors named "Fausto Arellano-Carbajal"

The mechanisms supporting regeneration and successful recovery of function have fascinated scientists and the general public for quite some time, with the earliest description of regeneration occurring in the 8th century BC through the Greek mythological story of Prometheus. While most animals demonstrate the capacity for wound-healing, the ability to initiate a developmental process that leads to a partial or complete replacement of a lost structure varies widely among animal taxa. Variation also occurs within single species based on the nature and location of the wound and the developmental stage or age of the individual.

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  • Two species of filarial worms, Dirofilaria immitis and Acanthocheilonema odendhali, were found in California sea lions, with a significant infection detected in adult females but very low in pups.
  • The study involved sampling 45 adult sea lions and 197 pups from different regions in the Gulf of California, revealing microfilariae in 77.78% of adults and only 0.51% of pups.
  • The infection prevalence and intensity varied by region, with higher rates in northern colonies, but overall, the sea lions showed no clinical signs of disease, indicating a need for further research on the impact of these infections on population health.
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  • Researchers explored the four mctp genes in zebrafish (mctp1a, mctp1b, mctp2a, and mctp2b), examining their structure, expression during development, and role in adult tissues.
  • They found that these genes are primarily active in the nervous and muscular systems, with different expression patterns starting from early development.
  • Knocking down mctp2b using CRISPR/Cas9 led to impaired embryonic development, indicating its crucial role during early stages.
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Ethnopharmacological Relevance: Psidium guajava and Tagetes erecta have been used traditionally to treat gastrointestinal parasites, but their active metabolites and mechanisms of action remain largely unknown.

Aim Of The Study: To evaluate the anthelmintic potential of Psidium guajava and Tagetes erecta extracts on Levamisole-sensitive and Levamisole-resistant strains of the model nematode Caenorhabditis elegans.

Materials And Methods: Aqueous extracts of Psidium guajava (PGE) and Tagetes erecta (TEE) were assayed on locomotion and egg-laying behaviors of the wild-type (N2) and Levamisole-resistant (CB193) strains of Caenorhabditis elegans.

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Brains organize behavior and physiology to optimize the response to threats or opportunities. We dissect how 21% O2, an indicator of surface exposure, reprograms C. elegans' global state, inducing sustained locomotory arousal and altering expression of neuropeptides, metabolic enzymes, and other non-neural genes.

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Genome sequence comparisons have highlighted many novel gene families that are conserved across animal phyla but whose biological function is unknown. Here, we functionally characterize a member of one such family, the macoilins. Macoilins are characterized by several highly conserved predicted transmembrane domains towards the N-terminus and by coiled-coil regions C-terminally.

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The genome of the nematode Caenorhabditis elegans encodes seven soluble guanylate cyclases (sGCs). In mammals, sGCs function as alpha/beta heterodimers activated by gaseous ligands binding to a haem prosthetic group. The principal activator is nitric oxide, which acts through sGCs to regulate diverse cellular events.

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Forty-two urine and 96 blood and serum samples were obtained from California sea lion (Zalophus californianus) pups from the Gulf of California during the 2000 reproductive season. Antibody prevalence to 13 serovars of Leptospira interrogans was determined by microagglutination tests (MAT); presence of pathogenic leptospires was detected by polymerase chain reaction (PCR). Samples with antibody titers > or = 1:25 or 115 bp fragments on ethidium bromidestained 1.

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