First Union Formation in Italy: The Role of Micro- and Macro-Level Economic Conditions.

In this paper, we use data from the 'Families and Social Subjects' survey conducted by the Italian National Institute of Statistics in 2016 to study the impact of micro- and macro-level economic conditions on first co-residential union formation. We aim to determine if and to what extent the probability of forming the first union is explained by individual labour market positions (e.g.

Adding up risks: Sexual debut and substance use among Italian university students.

Adolescence and youth are periods of great changes in an individual's life, during which experiencing first events of the transition to adulthood and, sometimes, violating social norms. Literature has identified an association of risk behaviours with timing of first sexual intercourse, but scant information is available about their relationship with the use of protection or the choice of a casual partner. This study focuses on the relation between initiation of risk behaviours (get drunk and drug use) and initiation of intercourse.

Melatonin and the Charlson Comorbidity Index (CCI): the Treviso Longeva (Trelong) study.

Introduction: It has been reported that elderly subjects have a compromised ability to produce melatonin nightly, and that reduced melatonin levels may be a risk factor for cancer. The purpose of this study was to evaluate the relationship between melatonin levels and chronic diseases in a cohort of elderly subjects using the Charlson comorbidity index (CCI).

Design: We performed a secondary data analysis of a longitudinal study of a representative, age-stratified, sample population.

Modulation of human longevity by SIRT3 single nucleotide polymorphisms in the prospective study "Treviso Longeva (TRELONG)".

Human sirtuins are seven proteins with deacetylase activity that are emerging as key modulators of basic physiological functions. Some evidence links SIRT3 to longevity in mammals. This study aimed to investigate whether variants within SIRT3 gene were associated to human longevity.

Insulin-like growth factor 1 receptor polymorphism rs2229765 and circulating interleukin-6 level affect male longevity in a population-based prospective study (Treviso Longeva--TRELONG).

Insulin-like growth factor 1 (IGF-1) signaling modulation has been associated with increased lifespan in model organisms, while high levels of circulating interleukin-6 (IL-6) are a marker of disability and mortality. In the prospective, population-based "Treviso Longeva"--TRELONG Study from Italy (n = 668, age range 70-105.5 years at baseline, followed for seven years) we investigated the effects of survival on the IGF-1 receptor (IGF-1R) gene polymorphism rs2229765, the IL-6 gene promoter polymorphism rs1800795, and plasma concentrations of IGF-1 and IL-6, alone or in combination.

Body mass index, cognition, disability, APOE genotype, and mortality: the "Treviso Longeva" Study.

Objectives: The concurrent contributions of dynamic, interrelated late-life parameters, such as body mass index (BMI), cognition, and physical functioning on mortality in the elderly are unclear, as is the influence of APOE genotype. We explored these measures in relation to 7-year mortality in long-lived Italian elderly.

Design: A representative, age-stratified, population sample.