Publications by authors named "Fatoumata I Ballo"
The discovery and development of transmission-blocking therapies challenge malaria elimination and necessitate standard and reproducible bioassays to measure the blocking properties of antimalarial drugs and candidate compounds. Most of the current bioassays evaluating the transmission-blocking activity of compounds rely on laboratory-adapted strains. Transmission-blocking data from clinical gametocyte isolates could help select novel transmission-blocking candidates for further development.
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- The cultivation of the malaria parasite has spurred research aimed at understanding it better and developing effective drug treatments.
- Current drug discovery efforts face challenges due to a lack of systems for cultivating its asexual blood stages, which are necessary for testing antimalarial drugs.
- The study improved the culture conditions for the malaria parasite, allowing for the screening of compounds like artemether and chloroquine to assess their antimalarial effectiveness.