Feasibility of post-exposure-prophylaxis with single-dose rifampicin and identification of high prevalent clusters in villages' hyperendemic for leprosy in Senegal.

Introduction: Senegal is a leprosy low-endemic country with nine villages known to be hyperendemic with a leprosy incidence rate above 1,000 per million inhabitants. We aim to implement a door-to-door screening strategy associated with the administration of a single-dose-rifampicin (SDR) as post-exposure prophylaxis (PEP) to household and social contacts in these villages and to identify spatial clustering and assess the risk of leprosy in population according to the physical distance to the nearest index-case.

Methods: From October/2020 to February/2022 active door-to-door screening for leprosy was conducted in nine villages.

Performance of Roche CAP/CTM HIV-1 qualitative test version 2.0 using dried blood spots for early infant diagnosis.

In the context of early infant diagnosis (EID) decentralization in sub-Saharan Africa, dried blood spot (DBS) is now widely used for HIV proviral DNA detection in resource-limited settings. A new version of CAP/CTM (version 2) has been introduced, recently by Roche Diagnosis as a new real-time PCR assay to replace previous technologies on qualitative detection of HIV-1 DNA using whole blood and DBS samples. The objective of this study was to evaluate CAP/CTM version 2 compared to CAP/CTM version 1 and Amplicor on DBS.

[Factors predictive of the probable occurrence of traumatic lesions at the level of the incisors. A case-control study of Senegalese adolescents].

Introduction: Knowledge of the factors influencing traumatic injuries of the anterior teeth is useful to prevent their occurrence. The aim of this case control study is to test the relationship between intrinsic and extrinsic factors and dental traumatism in adolescents.

Materials And Methods: Cases are 32 adolescent consulting for dental traumatism at the University Dental Clinic Dakar (Senegal).