Does α-lipoic acid therapeutically effective against experimentally induced-acute pulpitis in rats?

The purpose of the study was to investigate the therapeutic effects of α-lipoic acid (ALA) on an induced-acute pulpitis model in rats. Twenty-four Wistar albino rats were randomly divided into three groups: control, induced-acute pulpitis (PULP) and PULP + ALA groups. In the PULP and PULP + ALA groups, the crowns of the maxillary left incisors were removed horizontally.

Impacts of NaOCl and Irritrol irrigation solutions with/without autoclave sterilisation on the cyclic fatigue resistance of different nickel-titanium files.

This research aimed to examine the impact of NaOCl and Irritrol solutions with/without autoclave sterilisation on the cyclic fatigue resistance of ProTaper, WaveOne Gold and Reciproc NiTi files. Seventy files in every group were separated into seven subgroups (n = 10) according to irrigation solutions and sterilisation procedures. The mean and standard deviations of the time to fracture was calculated for each group, and the data statistical analysis was performed (P ≤ 0.

Anti-Inflammatory Effects of Melatonin and 5-Methoxytryptophol on Lipopolysaccharide-Induced Acute Pulpitis in Rats.

Aim: The aim of this study was to investigate the possible therapeutic impacts of two pineal hormones, melatonin and 5-methoxytryptophol (5-MTX), in a rat model of acute pulpitis by analyzing biochemical and histopathological parameters.

Methods: This research was done using 32 male and female Wistar albino rats with weight between 200 and 250 g. The rats were randomly divided into four groups: a control group (rats without any treatment), acute pulpitis (AP) group, AP+melatonin group, and AP+5-MTX group.

Protective effect of alpha-lipoic acid against apical periodontitis-induced cardiac injury in rats.

This study was designed to assess the possible protective effect of alpha-lipoic acid (ALA) on apical periodontitis (AP)-induced cardiac injury. Wistar albino rats were randomized into four groups: control; ALA; AP; and ALA + AP. Rats of the control and ALA groups were not endodontically treated, but saline and ALA (100 mg kg ) were administered.

Efficacy of different irrigation methods on dentinal tubule penetration of Chlorhexidine, QMix and Irritrol: A confocal laser scanning microscopy study.

The aim of this in vitro study was to compare the percentage of penetration of three final irrigant into the dentinal tubules after application of several irrigation techniques. Mandibular premolars were divided into nine groups (n:10): chlorhexidine (CHX) + conventional syringe irrigation (CI), CHX + EndoActivator (SI), CHX + Er,Cr:YSGG laser (LAI), QMix + CI, QMix + SI, QMix + LAI, Irritrol + CI, Irritrol + SI and Irritrol + LAI. Following irrigation, all roots were horizontally sectioned at 2 mm and 5 mm from the apex and examined using a confocal laser scanning microscopy.

Determination of the Minimum Inhibitory Concentrations of Alexidine and Chlorhexidine Against Enterococcus faecalis and Candida albicans: An In Vitro Study.

Introduction: The root canal system must be mechanically instrumented and chemically cleaned using various antimicrobial irrigants in a sequential manner or in combination for the elimination of necrotic pulp tissue and reducing the number of root canal bacteria. For this reason, new methods and materials are continuously being developed to achieve the objectives of endodontic treatment.

Materials And Methods: E.

Cone beam CT evaluation of mandibular molar root canal morphology in a Turkish Cypriot population.

Objectives: Microorganisms in untreated or overlooked root canals can cause endodontic failure or infection and inflammation. Therefore, clinicians should familiarize themselves with patient's root canal anatomy and morphology. The objective of this retrospective study was to analyze and characterize mandibular root canal morphology using cone beam computed tomography (CBCT) in a Turkish Cypriot population.