Publications by authors named "Fatma Hassan Ali"
Article Synopsis
- - Many patients with pulmonary diseases require mechanical ventilation (MV), which can lead to ventilation-induced lung injuries (VILIs) due to stress on the delicate lung epithelium, especially in those with acute respiratory distress syndrome (ARDS).
- - Researchers propose a new method to protect epithelial cells during MV by altering their cytoskeletal structure, testing the anti-inflammatory drugs dexamethasone (DEX) and transdehydroandrosterone (DHEA) for their effects on cell survival under stress.
- - Their findings show that preexposing cells to DEX or DHEA significantly reduces cell death caused by MV, suggesting a potential treatment approach for ARDS in patients, including those affected by COVID-
Parallel plate flow chambers are widely used to expose cultured cells to physiological flows for the investigation of a variety of diseases. These applications usually involve the generation of continuous and steady fluid flow over cell monolayers for extended durations, usually a few days. Another technique is to generate a fast high-stress wave over the cells to see the immediate effect of flow-induced stresses.
View Article and Find Full Text PDF