Ophthalmic manifestations of paranasal sinus disease: a clinical grading system.

Background: Ophthalmic complications are common manifestations of paranasal sinus disease. We propose a clinical grading system to standardize the category, treatment, and outcome of these complications.

Methods: Forty-two patients with paranasal sinus disease-induced ophthalmic complications were included in the study.

The role of caspase activation and mitochondrial depolarisation in cultured human apoptotic eosinophils.

Caspases are key intracellular molecules in the control of apoptosis, but little is known concerning their relative contribution to the cascade of events leading to eosinophil apoptosis. We examined caspase-3, -8, and -9 activities in receptor ligation dependent apoptosis induction in the cultured eosinophils (CE). CE cultured alone for 48 hours exhibited constitutive apoptosis (12% ± 1.

Modulation of dendritic cell activation chemokines and cellular injury.

Dendritic cells (DC) are professional antigen presenting cells expressing MHC class II, derived from a common marrow precursor. They are motile, diffused and have a spidery shape with many long cytoplasmic processes. The aim of this project was to test the hypothesis that cellular injury induces the activation and functional maturation of DC.

Iatrogenic cholesteatoma in children with OME in a training program.

Purpose: To report the occurrence of cholesteatoma following myringotomy and insertion of ventilating tube (VT) in a residency training program.

Materials And Methods: Nine hundred and eighty-four children who were operated for grommet insertion with or without adenotonsillectomy during the year 1999-2003 were included in the study. Children were divided into two groups: group 1 (648 children) operated by residents and group 2 (305 children) operated by consultant.