Increased Risk of the rs11279109 Polymorphism for CHD among the Kuwaiti Population.

Background: Coronary heart disease (CHD) is among the leading causes of death in Kuwait. This case-control study investigated the genetic association of rs11279109 with CHD in Kuwaitis.

Methods: The polymorphism was genotyped in 734 Kuwaiti samples by direct amplification.

Association of the insertion allele of the common ACE gene polymorphism with type 2 diabetes mellitus among Kuwaiti cardiovascular disease patients.

Background And Objectives: The D allele of the common angiotensin-converting enzyme (ACE) I/D gene polymorphism (rs4646994) predisposes to type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). However, results on which allele predisposes to disease susceptibility remain controversial in Asian populations. This study was performed to evaluate the association of the common ACE I/D gene polymorphism with both T2DM and CVD susceptibility in an Arab population.