Possible protective effect of platelet-rich plasma on a model of cisplatin-induced nephrotoxicity in rats: A light and transmission electron microscopic study.

Background: Cisplatin (Cis), is a potent chemotherapeutic drug. However, Cis nephrotoxicity is high, thus limiting its use. Platelet-rich plasma (PRP) is an autologous product, easy to get from blood centrifugation.