Doxorubicin-loaded methoxy-intercalated kaolinite as a repackaging of doxorubicin for an enhanced breast cancer treatment: in vitro and in vivo investigation.

Doxorubicin is one of the most common wide-spectrum chemotherapeutics. However, its efficacy is limited due to off-target accumulation and selectivity issues. In this study, we compared the anti-cancer effect and biocompatibility of KaoliniteMeOH-Dox, a doxorubicin repackaging, to doxorubicin monotherapy.

Radiation sensor based on a 1D-periodic structure infiltrated by (B-co-MP) a conjugated copolymer.

In this study, a novel gamma-ray radiation sensor has been developed depending on a 1D photonic crystal (1D-PhC). Based on porous silicon (PSi) layer that has been penetrated by a conjugated copolymer (B-co-MP) which consists of BEHP-PPV and MEH-PPV, with a fractional ratio of 60:40. The suggested method for the development of the dosimeter is based on the shift of photonic band-gap to shorter wavelengths, where exposure to gamma-ray radiation at doses ranging from 0 to 20 kGy alters the refractive index of the (B-co-MP) copolymer.

Angular surface plasmon resonance-based sensor with a silver nanocomposite layer for effective water pollution detection.

For sensing various samples of polluted water and various sodium chloride concentrations using an angular surface plasmon resonance (ASPR), we have introduced a conventional structure and a hybrid heterostructure in the current research. The suggested structures are composed of silver metal, dielectric layers, silver nanocomposite, and a sensing medium. The reflectance spectra of all structures in the visible region were obtained through the utilization of the transfer matrix method by using the angular interrogation method depending on the Kretschmann configuration.

Monitoring and simulation of the fuel irradiation behavior in nuclear reactors based on phononic crystal structure.

We have presented in the current work a novel idea for simulating the irradiation behaviors of the nuclear fuel pellets in nuclear reactors by using a one-dimensional defective phononic crystal (1D-DPnC) design was presented. The transmission spectra of the incident mechanical waves were considered basic data for expressing the characteristics of different nuclear fuel-pellets. Herein, the density, sound speed, and Young's modulus of the fuel-pellets represent the key parameters that are influenced by the irradiation behaviors of these pallets.

A doped-polymer based porous silicon photonic crystal sensor for the detection of gamma-ray radiation.

In this research, a theoretical investigation of the one-dimensional defective photonic crystals is considered for the detection of gamma-ray radiation. Each unit cell of the considered one-dimensional photonic crystals (1D PhCs) is composed of two layers designed from porous silicon infiltrated by poly-vinyl alcohol polymer doped with crystal violet (CV) and carbol fuchsine (CF) dyes (doped-polymer) with different porosity. In addition, a single layer of doped-polymer is included in the middle of the designed 1D PhCs to stimulate the localization of a distinct resonant wavelength through the photonic band gap.

Morphologic design of nanostructures for enhanced antimicrobial activity.

Despite significant progress in synthetic polymer chemistry and in control over tuning the structures and morphologies of nanoparticles, studies on morphologic design of nanomaterials for the purpose of optimizing antimicrobial activity have yielded mixed results. When designing antimicrobial materials, it is important to consider two distinctly different modes and mechanisms of activity-those that involve direct interactions with bacterial cells, and those that promote the entry of nanomaterials into infected host cells to gain access to intracellular pathogens. Antibacterial activity of nanoparticles may involve direct interactions with organisms and/or release of antibacterial cargo, and these activities depend on attractive interactions and contact areas between particles and bacterial or host cell surfaces, local curvature and dynamics of the particles, all of which are functions of nanoparticle shape.

Cytotoxicity and genotoxicity of gold nanorods assisted photothermal therapy against Ehrlich carcinoma in-vivo.

Aim: Preparation of pegylated gold nanorods (PEG-AuNRs) that are capable of converting near infrared (NIR) light into heat. Evaluation of cancer therapeutic efficacy and long-term toxicity of the proposed photothermal therapy in comparison with other conventional modalities.

Materials And Methods: Prepared PEG-AuNRs were characterized by measuring their absorption spectra, zeta potential, and transmission electron microscope (TEM).

Defect mode tunability based on the electro-optical characteristics of the one-dimensional graphene photonic crystals.

New (to the best of our knowledge) photonic crystal optical filters with unique optical characteristics are theoretically introduced in this research. Here, our design is composed of a defect layer inside one-dimensional photonic crystals. The main idea of our study is dependent on the tunability of the permittivity of graphene by means of the electro-optical effect.