Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience.

Background/aims: Solitary rectal ulcer syndrome (SRUS) can be overlooked, diagnosed late, or misdiagnosed, particularly in childhood. This study reviewed the 13-year experience of the authors' institution to increase clinicians' awareness of SRUS in the presence of symptoms. This paper reports the endoscopic and histopathological findings in children presenting with hematochezia.

The effect of anxiety and depression levels of children with celiac disease on quality of life.

Purpose: This study was conducted to examine the effect of anxiety and depression levels on quality of life in children with celiac disease.

Design And Method: This descriptive and correlational study was conducted with 98 children diagnosed with celiac disease who applied to the pediatric outpatient clinic of a university hospital in Eastern Anatolia between September 2021 and August 2022. Data were collected using the State-Trait Anxiety Scale, Depression Scale, and Quality of Life Scale through face-to-face interviews conducted by the researchers.

Liver Transplantation for Hepatocellular Carcinoma in Patients with Inherited Metabolic Liver Diseases: A Single-Center Analysis.

Background/aims: Liver transplantation is an acceptable treatment for some selected hepatocellular carcinoma. We report our experience of 6 patients with liver transplantation for hepatocellular carcinoma with background inherited metabolic disease.

Materials And Methods: This is a single-center retrospective, descriptive study.

Knowledge regarding celiac disease among healthcare professionals, patients and their caregivers in Turkey.

Background: Celiac disease (CD) is one of the most prevalent chronic disorders. The clinical manifestations of CD are diverse and may present with gastrointestinal findings, extra-intestinal findings or no symptoms. Although there has been a marked increase in the prevalence of CD in the past 30 years, up to 95% of patients with CD remain undiagnosed.

Burnout, mental health symptoms, and empathy in healthcare workers who care for children treated in a liver transplant center.

Objective: The healthcare workers in pediatric liver transplantation units are exposed to various stresses; however, their burnout has not been clarified yet. This study aimed to determine burnout, psychological symptoms and empathy levels in healthcare workers, to examine the relationship between these variables and to investigate the predictors of burnout.

Method: This cross-sectional study was conducted on healthcare workers in Turgut Özal Medical Center Pediatric Liver Transplant Institute.

Factors Associated with Low Bone Mineral Density at the Time of Diagnosis in Children with Celiac Disease.

Objective: It has been reported that bone mineral density (BMD) is decreased in children with Celiac disease (CD) compared to their healthy peers. The aim of this study was to reveal possible risk factors for low BMD in Turkish children newly diagnosed with CD.

Methods: Eighty-six patients (2-18 years old) with CD were included in this retrospective study.

Is There a Predictive Factor for an Association with Autoimmune Glandular Disease in Children Diagnosed with Celiac Disease?

Objective: A close relationship has been suggested between Celiac disease (CD) and glandular autoimmunity. The aim of this study was to determine the predictive factors for autoimmune glandular disease (AGD) in children with CD.

Methods: The study included 228 pediatric patients, diagnosed with CD between 2010 and 2019.

Single-center experience in management of progressive familial intrahepatic cholestasis.

Background And Study Aims: Progressive familial intrahepatic cholestasis (PFIC) is an autosomal recessively inherited disease that causes intrahepatic-hepatocellular cholestasis. PFIC constitutes approximately 10-15% of cholestatic liver diseases in children. The aim of this study is to draw attention to this group of diseases, which pose a higher risk, in societies where consanguineous marriage is more common, and to share our experiences since the studies in the literature, regarding this group of diseases are case series with small number of patients.

Prevalence of Familial Mediterranean Fever in Children with Cryptogenic Cirrhosis.

Background: Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by abdominal and chest pain and recurrent fever due to inflammation in the serosal membranes such as peritoneum, pleura and synovia. In FMF, recurrent inflammatory cytokine production may lead to cirrhosis. The aim of this study was to determine the prevalence of FMF in children with cryptogenic cirrhosis and it was found to be high, to add FMF among the etiological causes of cirrhosis.

Pediatric Hepatocellular Carcinoma.

Purpose: Pediatric hepatocellular carcinoma is rarely seen in childhood. It constitutes approximately 1% of childhood solid organ malignancies. Pediatric hepatocellular carcinoma is the second most common malignant liver tumor after hepatoblastoma in children.

Infection risk after paediatric liver transplantation.

Infections after liver transplantation (LT), despite prophylactic therapy, are still important causes of morbidity and mortality in children. Although underlying disease and immunosuppression along with the complexity of LT procedure are the major predispositions to infections, there still might be under recognised factors predisposing infections in paediatric LT. In this study, we retrospectively analysed the risk factors of bacterial, viral, and fungal infections after LT in a series of 167 children (median =5 yr.

Nutritional assessment of children with Wilson's disease: single center experience.

Aim: Nutritional status was accepted as a prognostic marker in children with chronic liver disease. In the literature, we aimed to retrospectively investigate 94 Wilson patients followed in our center due to the lack of studies investigating the frequency and prognostic effects of malnutrition and micronutrient deficiency in Wilson's patient.

Material And Methods: Our studies included 94 Wilson's disease children in the Department of Child Gastroenterology, Hepatology and Nutrition of Inonu University Faculty of Medicine between 2006-2017.

The effects of iron and zinc status on prognosis in pediatric Wilson's disease.

Objectives: Wilson's disease (WD) is a metabolic disorder leading to hepatic and extrahepatic copper deposition. Several studies have reported that besides copper (Cu), iron (Fe) and zinc (Zn) are also accumulated at varying levels in various tissues in WD. However, there is not an adequate number of studies investigating the effects of Fe and Zn status on WD presentation and prognosis.

Pediatric Wilson's disease: findings in different presentations. A cross-sectional study.

Background: Wilson's disease (WD) may present with different manifestations: from an asymptomatic state to liver cirrhosis. Here, we aimed to evaluate clinical presentations and laboratory findings and prognoses among WD cases.

Design And Setting: Cross-sectional study based on patients' records from the university hospital, İnönü University, Malatya, Turkey.

Torsion of a wandering spleen in an adolescent with Gaucher disease.

A wandering spleen is a rare condition characterized by the malposition of the spleen due to laxity or absence of its supporting ligaments. Although Gaucher disease generally presents with massive splenomegaly, which one of the predisposing causes of a wandering spleen, literature shows only one report of a wandering spleen in a child with Gaucher disease. In this case presentation, a 13-year-oldadolescent with Gaucher disease on enzyme replacement treatment was presented, who was detected having an abdominal mass on a routine visit and diagnosed with partial torsion of a wandering spleen associated with left lobe hypoplasia of the liver.