Molecular cloning and in silico analysis of chalcone isomerase from Polygonum minus.

Background: Chalcone isomerase (CHI; EC 5.5.1.

Recent advancement of engineering microbial hosts for the biotechnological production of flavonoids.

Flavonoids are polyphenols that are important organic chemicals in plants. The health benefits of flavonoids that result in high commercial values make them attractive targets for large-scale production through bioengineering. Strategies such as engineering a flavonoid biosynthetic pathway in microbial hosts provide an alternative way to produce these beneficial compounds.