[Smoking in People Living with HIV (PLHA) and followed up in the Outpatient Department of the Hospital Fann of Dakar].

Introduction: PLHA who smoke have twice the never-smoker mortality rate and have an increased risk of developing non-AIDS diseases. The prevalence of tobacco smoking is higher among PLHA than in the general population. The purpose of this study was to assess the prevalence of smoking among PLHA, to describe the clinical and spirometric features of smokers and ex-smokers and to assess their knowledge and attitudes toward smoking.

Mitochondrial DNA Mutations and Rheumatic Heart Diseases.

Acute rheumatic fever (ARF) is an autoimmune disease affecting the heart-valve endocardium in its final stage. Although rare in developing countries, ARF persists in third-world countries, particularly Senegal, where rheumatic heart diseases (RHDs) are the most common pediatric cardiovascular pathology. This study aimed to investigate mutations in in ARF and RHD in Senegalese patients.

Somatic Mitochondrial Mutations in Oral Cavity Cancers among Senegalese Patients.

Background: Somatic mutations affecting the mitochondrial DNA (mtDNA) have been frequently observed in human cancers and proposed as important oncological biomarkers. However, the exact mtDNA mutations that is responsible for the pathogenesis of cancer remains unclear. The aim of this study was to investigate somatic mutations in the MT-CYB and D-Loop regions of mitochondrial DNA (mtDNA) in oral cavity cancers from Senegalese patients.

[Radiological features of microscopy-positive pulmonary tuberculosis in patients in the Pneumology Department at the National University Hospital, Fann, Dakar (Sénégal)].

This study aimed to determine the radiological features of microscopy-positive pulmonary tuberculosis (TB). We conducted a retrospective study, analyzing radiographical imaging of patients with microscopy-positive pulmonary tuberculosis between 15 November 2015 and 15 March 2016. The medical records of 66 patients meeting the inclusion criteria were selected, 81.