Publications by authors named "Fatimah Alkhunaizi"

Article Synopsis
  • Cardiogenic shock (CS) is a serious condition characterized by insufficient cardiac output, resulting in tissue damage and organ dysfunction, with a high mortality rate.
  • The management of CS has evolved significantly, particularly with the use of temporary mechanical circulatory support (tMCS) devices, necessitating an understanding of patient assessment and treatment strategies in ICUs.
  • The article reviews causes, pathophysiology, diagnosis, and staging of CS, emphasizing the importance of tailored medical and mechanical therapies based on the type and severity of heart failure in affected patients.
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Background: Klüver-Bucy syndrome (KBS) is a rare neuropsychiatric disorder, and it can be associated with a variety of neurological disorders. It is characterized by visual agnosia, placidity, hyperorality, hypersexuality, dietary changes, amnesia, and hypermetamorphosis. KBS is mainly a clinical diagnosis, with at least three symptoms sufficient to diagnose the condition.

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Article Synopsis
  • Financial barriers significantly affect access to heart transplantation, with patients incurring costs for hospitalization, medications, and travel.
  • A study analyzed 1,000 GoFundMe campaigns for heart transplants, ultimately including 634 campaigns, mostly for white males and adults, with about 15% raising no funds.
  • The research underscores the financial hardships faced by patients and calls for advocacy to enhance equitable access and coverage for heart transplantation across society.
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Background: Detecting right heart failure post left ventricular assist device (LVAD) is challenging. Sensitive pressure-volume loop assessments of right ventricle (RV) contractility may improve our appreciation of post-LVAD RV dysfunction.

Methods: Thirteen LVAD patients and 20 reference (non-LVAD) subjects underwent comparison of echocardiographic, right heart cath hemodynamic, and pressure-volume loop-derived assessments of RV contractility using end-systolic elastance (Ees), RV afterload by effective arterial elastance (Ea), and RV-pulmonary arterial coupling (ratio of Ees/Ea).

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Late right heart failure (LRHF) following left ventricular assist device (LVAD) implantation remains poorly characterized and challenging to predict. We performed a multicenter retrospective study of LRHF in 237 consecutive adult LVAD patients, in which LRHF was defined according to the 2020 Mechanical Circulatory Support Academic Research Consortium guidelines. Clinical and hemodynamic variables were assessed pre- and post-implant.

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Article Synopsis
  • Right ventricular (RV) failure is a significant health issue that leads to high rates of complications and death, and when medication fails, mechanical circulatory support (MCS) options should be explored.
  • Recent advancements in temporary right-sided MCS are emerging, with new devices being designed that effectively unload the RV and improve blood flow by directly aspirating blood.
  • Innovative single-access MCS devices are in development, allowing for less patient mobility restriction, and a notable new device called the PERKAT RV is being tested in human trials.
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A 46-year-old man was admitted with non-ST elevation myocardial infarction and newly diagnosed acutely decompensated heart failure. Echocardiogram demonstrated left ventricular ejection fraction of 30% with basal inferior and inferolateral akinesis. Coronary angiography showed mild diffuse coronary artery disease and an anomalous right coronary artery arising from the left coronary cusp.

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Objectives: We evaluated the impact of preoperative liver function on early and 1-year postoperative outcomes in patients supported with a left ventricular assist device (LVAD) and subsequent evolution of liver function markers.

Methods: A retrospective multicentre cohort study was conducted, including all patients undergoing continuous-flow LVAD implantation. The Model for End-stage Liver Disease (MELD) score was used to define liver dysfunction.

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