A new extension of Burr-Hatke exponential distribution with engineering and biomedical applications.

In this study, the Topp-Leone family of distribution approach was used to modify the Burr Hatke Exponential distribution to provide adequate fits for some engineering and health data which previous existing distributions in the family of Burr Hatke Exponential have failed to do. The new distribution improves the robustness of Burr Hatke Exponential distribution by making it capable of modeling emerging new world complex data with varying features, possesses greater capacity and flexibility to model lifetime data, has better goodness of fit. Some mathematical properties of the derived distribution such as quantile function, moments, order statistics, entropies, etc were obtained and discussed.

Construction of improved comprehensive classes of estimators for population distribution function.

The primary purpose of this article is to examine the issue of estimating the finite population distribution function from auxiliary information, such as population mean and rank of the auxiliary variables, that are already known. In order to better estimate the distribution function (DF) of a finite population, two improved estimators are developed. The bias and mean squared error of the suggested and existing estimators are derived up to the first order of approximation.

The quasi-xgamma frailty model with survival analysis under heterogeneity problem, validation testing, and risk analysis for emergency care data.

Frailty models are important for survival data because they allow for the possibility of unobserved heterogeneity problem. The problem of heterogeneity can be existed due to a variety of factors, such as genetic predisposition, environmental factors, or lifestyle choices. Frailty models can help to identify these factors and to better understand their impact on survival.

Effects of Rhazya Stricta plant organic extracts on human induced pluripotent stem cells derived neural stem cells.

Rhazya Stricta (R. stricta) has been employed as a natural remedy for several diseases for centuries. Numerous studies revealed that R.

Structural and Phylogenetic Analysis of Protein Reveals New Insights into Its Role in Emerging and Re-Emerging Diseases in Mammals.

Chemokine receptor type 4 () is a G protein-coupled receptor that plays an essential role in immune system function and disease processes. Our study aims to conduct a comparative structural and phylogenetic analysis of the protein to gain insights into its role in emerging and re-emerging diseases that impact the health of mammals. In this study, we analyzed the evolution of genes across a wide range of mammalian species.

Modifying of calcareous soil with some acidifying materials and its effect on (L.) growth.

Calcareous soils contain a high concentration of calcium carbonate (CaCO), which influences soil properties related to plant growth. Humic acid (HA) and ammonium molybdate (AM) were added as treatments for calcareous soils at concentrations of 0.1, 0.

Dynamic cytosolic foci of DPPA4 in human pluripotent stem cells.

DPPA4 is essential for the pluripotent stem cell state, yet its function is poorly understood. DPPA4 is localized in the nucleus, where it is associated with active chromatin. We now report that it is also present in the cytosol, where it appears as diffused clouds, distinct foci and sometimes as spaghetti-like structures.

Molecular Evolution of the Activating Transcription Factors Shapes the Adaptive Cellular Responses to Oxidative Stress.

Reactive oxygen species (ROS) play an essential part in physiology of individual cell. ROS can cause damage to various biomolecules, including DNA. The systems that have developed to harness the impacts of ROS are antique evolutionary adaptations that are intricately linked to almost every aspect of cellular function.

A Comprehensive Analysis of Unique and Recurrent Copy Number Variations in Alzheimer's Disease and its Related Disorders.

Background: Copy number variations (CNVs) play an important role in the genetic etiology of various neurological disorders, including Alzheimer's disease (AD). Type 2 diabetes mellitus (T2DM) and major depressive disorder (MDD) were shown to have share mechanisms and signaling pathways with AD.

Objective: We aimed to assess CNVs regions that may harbor genes contributing to AD, T2DM, and MDD in 67 Saudi familial and sporadic AD patients, with no alterations in the known genes of AD and genotyped previously for APOE.

Specialty Preferences and the Factors Influencing Them Among Pre-Clerkship Medical Students: The First Study from Alfaisal University-College of Medicine, Saudi Arabia.

Aim: To explore the specialty preferences and the factors influencing them among pre-clerkship (second-year and third-year) medical students at Alfaisal University-College of Medicine, Riyadh, Saudi Arabia.

Methods: An online, anonymous, cross-sectional, self-rating survey was administered. The survey explored socio-demographical data, specialty preferences and the factors influencing such preferences.