Publications by authors named "Fatima-Zahra Azzaoui"
Article Synopsis
- Recent research highlights a significant difference in gut microbiota (GM) between children with autism and those without, suggesting that gastrointestinal issues are common among autistic individuals.* ! -
- A systematic review of studies from 2010 to 2022 found evidence linking autism to vitamin A deficiency (VAD), indicating that VAD might contribute to the development of autism, particularly when experienced in early life.* ! -
- The findings suggest that changes in GM could serve as potential biomarkers for autism and highlight the need for further studies on vitamin A supplementation as a possible intervention to reduce autism symptoms.* !
Autism spectrum disorder (ASD) includes a heterogeneous group of complex neurodevelopmental disorders characterized by atypical behaviors with two core pathological manifestations: deficits in social interaction/communication and repetitive behaviors, which are associated with disturbed redox homeostasis. Modulation of cellular resilience mechanisms induced by low levels of stressors represents a novel approach for the development of therapeutic strategies, and in this context, neuroprotective effects of a wide range of polyphenol compounds have been demonstrated in several in vitro and in vivo studies and thoroughly reviewed. Mushrooms have been used in traditional medicine for many years and have been associated with a long list of therapeutic properties, including antitumor, immunomodulatory, antioxidant, antiviral, antibacterial, and hepatoprotective effects.
View Article and Find Full Text PDFAutism spectrum disorder (ASD) is a group of neurodevelopmental disorders defined by a lack of social behaviors, repetitive behaviors and nonverbal interactions, such as limited eye contact, facial expression, and body gesturing. It is not a single condition, but rather a multi-factorial disorder caused by hereditary and non-genetic risk factors, as well as their interaction. According to several studies, the gut microbiota may have a role in the pathophysiology of autism spectrum disorder.
View Article and Find Full Text PDFArticle Synopsis
- Alzheimer's disease (AD) is increasingly threatening African populations due to longer life expectancies, prompting research into natural products like catechin and dimeric procyanidins for potential cognitive protection.
- adult male Wistar rats were used in experiments where Aβ was injected to mimic AD, followed by treatments with melatonin or the extract to assess cognitive abilities and oxidative stress levels.
- Results showed that the extract reduced cognitive impairments and oxidative stress induced by Aβ, suggesting its potential neuroprotective effects are comparable to melatonin, but further pharmacological studies are needed to validate these findings.
Introduction: Psychopharmacology today faces serious challenges, especially related inappropriate drug choices, abuse and resulting side effects. The aim of this pharmacy based study in the City of Tiflet was to profile the prescription and usage patterns of psychotropic drugs.
Methods: This study was conducted in the pharmacies of the City of Tiflet (Morocco).