Publications by authors named "Fatima Zahra Mernissi"

Primary cutaneous adenoid cystic carcinoma (PCACC) is a rare, slow-growing adnexal skin tumor with about 250 documented cases. We present a case involving a 66-year-old woman who was treated with ovulation inductors 30 years ago and underwent surgeries for meningioma 20 years ago and invasive galactophoric adenocarcinoma of the left breast 12 years ago. She presented with a gradually enlarging, solid, skin-colored tumor on her scalp, located along an old surgical scar initially diagnosed as a keloid by her surgeon.

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Introduction: Cutaneous squamous cell carcinoma (cSCC) is the second most common skin cancer, accounting for 20% of malignant skin tumors. Dermoscopy is a very useful tool for diagnosing cSCC, and its findings are confirmed through histopathological studies.

Objectives: to describe the different dermoscopic structures of invasive cSCC and investigate their association with the clinical form and histopathological grade of differentiation.

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Article Synopsis
  • Malignant melanocytic matricoma (MMM) is a very rare type of skin cancer characterized by specific cells known as epithelial cells with matrical differentiation and dendritic melanocytes; only 11 cases have been documented in medical literature.
  • A case study reported involves an 86-year-old woman, where histological examination revealed a tumor with deep infiltration but no connection to the epidermis.
  • Immunohistochemical tests indicated that the tumor cells expressed certain proteins while the typical markers for melanoma were absent, confirming the diagnosis of MMM rather than other skin cancers like melanoma or basal cell carcinoma.
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Introduction: Frontal fibrosing alopecia (FFA) is a form of primary lymphocytic scarring alopecia characterized by a progressive recession of the fronto-temporal hairline. Although the clinical presentation of FFA is very typical, biopsy for histopathological examination is still recommended to confirm the diagnosis. Currently, a growing number of skin and mucosal inflammatory diseases are diagnosed with modern noninvasive techniques such as dermoscopy without the necessity of a biopsy.

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Mohs micrographic surgery (MMS) is a technique allowing for intraoperative histologic assessment of surgical margin of malignant tumors. This study aims to highlight the role of MMS in the achievement of radical healing of basal cell carcinoma (BCC) in our patients. We conducted a study of 29 patients with basal cell carcinoma of the face over a period of 5 years.

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The erysipelas is a bacterial infection most frequently due to (85% of cases) streptococcus β-hemolytic of group A (SGA), resulting in non-necrotizing dermo-hypodermitis. Many factors may play a role in its occurrence such as general factors: diabetes, immunosuppression, chemotherapy, radiotherapy as well as locoregional ports of entry such as leg ulcer, an insect bite, intertrigo. The occurrence of erysipelas associated with recurrent squamous cell carcinoma after radiochemotherapy is exceptional, requiring early treatment of dermo-hypodermitis as well as suitable and multidisciplinary management of the carcinoma.

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Harlequin's syndrome is a rare dysautonomic syndrome of the face characterized by sweating with flush of one side and anhidrosis of the contralateral side. Mostly idiopathic although several secondary cases have been reported in the literature, the purpose of the treatment is mainly aesthetic and functional. We report the case of a patient having harlequin syndrome in its idiopathic form with a literature review.

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Pemphigus vegetans is a rare form of pemphigus. It accounts for only 2%. There is a broad range of effective options available to treat this disease: topical and/or oral corticosteroids as first-line treatment, immunosuppressants such as Azathioprine, Cyclosporine, Methotrexate, Cyclophosphamide and Mycophenolate mofetil to reduce the side effects of steroids.

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Introduction: Tinea capitis is a scalp infection caused by different fungi. Etiological diagnosis is based on suggestive clinical findings and confirmation depends on the fungus growth in culture. However, it is not always possible to perform this test due to lack of availability.

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Article Synopsis
  • A study was conducted in Fez, Morocco, to analyze the dermoscopic features of trichostasis spinulosa (TS) and its correlation with clinical characteristics and treatment responses among patients.
  • The results showed that indicators like severe hair retention and dermoscopic blackhead-like structures were common, with a majority of patients having vellus hairs and follicular keratosis identified as orange-yellowish keratotic plugs.
  • The findings suggest that dermoscopy enhances diagnosis accuracy for TS and proposes a new classification system that has therapeutic relevance, particularly emphasizing differences in treatment responses based on certain dermoscopic features.
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Background: Herein, we report an unusual case of multifocal glomus tumors in the same hand in a patient suffering from neurofibromatosis type 1.

Case Presentation: The patient was a 37-year-old Moroccan woman, suffering from neurofibromatosis type 1, with intense pain in the fingers, successfully treated with the excision of the tumors. Histology of the lesions confirmed the diagnosis of glomus tumor.

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Background: Glomus tumor is a benign and vascular hamartoma that originates from the neuromyoarterial cells of the normal glomus apparatus in the reticular dermis. The etiology of glomus tumors is unknown. It usually presents as a small, slightly raised, bluish or pinkish-red, painful nodule of the fingertips and the pulp.

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Article Synopsis
  • Superficial circumscribed lymphangiomas are generally benign growths commonly found in the neck and face, mostly seen in children.
  • A clinical case is presented involving an elderly man with a lymphangioma on his tongue, requiring differential diagnosis from conditions like Kaposi's disease and solid tumor metastases.
  • The diagnosis was confirmed through a biopsy, and since the patient wasn't experiencing discomfort, the decision was made to monitor the condition rather than proceed with treatment.
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The rainbow pattern is currently a subject of debate, it is considered the specific dermoscopic pattern of Kaposi sarcoma. We present in this research correspondence a review of 700 dermoscopic figures of different biopsy-proven skin diseases in our department of dermatology of the Hospital Hassan II of Fez. All the lesions were localized to the limbs except for one lesion of atrophic scar that was localized on the left shoulder.

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Background: Glomus tumors are rare, benign, vascular neoplasms arising from the glomus body. Although they can develop in any part of the body, they commonly do so in the upper extremities, most frequently subungual areas. They can be either solitary or multiple.

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