Publications by authors named "Fatima S Alwan"
Objectives: Thrombotic complications after total pancreatectomy with islet autotransplantation (TPIAT) are common. However, the systemic changes to coagulation in the perioperative period have not been well studied. Our objective was to evaluate the derangements in coagulation in the perioperative period for this procedure.
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- Venovenous extracorporeal membrane oxygenation (VV-ECMO) is a supportive treatment for adults with severe COVID-19-related ARDS, achieving hospital survival rates of 62%-74%, comparable to other conditions requiring ECMO.
- A study analyzed 46 patients receiving ECMO in Minnesota from March to November 2020, finding that 30 (65.2%) survived for 60 days, with factors such as older age, lower oxygenation levels, and higher organ failure scores linked to higher mortality risk.
- After initiating ECMO, increased mortality was correlated with longer antibiotic use, more blood transfusions, elevated white blood cell counts, and changes in platelet levels, indicating that infections significantly impact survival outcomes
Article Synopsis
- Postoperative gastrointestinal bleeding (GIB) occurs in 12.4% of patients who undergo total pancreatectomy with islet autotransplant (TPIAT), with a median onset of 17 months after surgery.
- The main causes of GIB included anastomotic ulcers (35%) and various other conditions, while about 29% had no clear cause identified even after diagnostic procedures like endoscopy.
- Intervention rates were significant, with 30% of patients requiring treatments ranging from endoscopic procedures to surgery, and those experiencing GIB had a higher mortality rate compared to those who did not (15% vs. 5%).
Objectives: This study aimed to quantify the prevalence of venous thromboembolic (VTE) events in patients with pancreatitis requiring hospitalization and its impact on outcomes.
Methods: Adult patients admitted from 2011 to 2018 for pancreatitis were identified. Every admission for pancreatitis in the first year after diagnosis was evaluated for a VTE (pulmonary embolism, deep vein thrombosis, or mesenteric vessel thrombosis) within 30 days of discharge.
Severe acute respiratory distress syndrome (ARDS) unresponsive to conventional intensive care unit (ICU) management is an accepted indication for venovenous extracorporeal membrane oxygenation (V-V ECMO) support. The frequency with which patients with coronavirus disease 2019 (COVID-19) pneumonia are selected for V-V ECMO has not been described. This was a cohort study including all patients placed on either V-V ECMO or venoarteriovenous ECMO at the four adult ECMO Centers of Excellence.
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