Possible involvement of the lipoxygenase and leukotriene signaling pathways in cisplatin-mediated renal toxicity.

Purpose: The present study examined the possible involvement of the lipoxygenase (LOX) pathway in cisplatin (CPT)-induced nephrotoxicity.

Methods: Wistar albino rats were challenged with CPT IP injection (7.5 mg/kg) and were sacrificed after one week.

attenuates oxidative and inflammatory processes in acetic acid-induced ulcerative colitis.

The pathogenesis of ulcerative colitis (UC) has been associated with a weakened antioxidant capacity and increased inflammatory processes. is traditionally used for the treatment of inflammatory diseases due to its antioxidant and anti-inflammatory properties. The present study aimed to evaluate the effects of on an experimental rat model of UC.