Publications by authors named "Fatima Kassymbekova"

Article Synopsis
  • Cervical cancer, mainly caused by human papillomavirus (HPV), is a significant health issue in Kazakhstan, where a previous HPV vaccination pilot program was halted due to parental refusals, but plans to restart it are underway.
  • A study conducted from December 2022 to May 2023 surveyed 1,189 healthcare professionals using a self-administered questionnaire to assess their knowledge, attitudes, and barriers regarding HPV and the HPV vaccine.
  • Results showed an average knowledge score of 11 out of 18, with physicians scoring higher than nurses; 72.6% were willing to recommend the vaccine, and higher knowledge and awareness were linked to increased likelihood of recommendation, while barriers included public mistrust and fear of
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Article Synopsis
  • Cancer is the second leading cause of death globally and has become a growing issue in Kazakhstan, particularly in Almaty, where common cancers include lung and prostate cancers in men and breast and cervical cancers in women.
  • From 2017 to 2021, the study found that these cancers contributed to a total disability-adjusted life years (DALYs) burden of 25,016.60 in 2021, with the majority of this burden coming from mortality rather than disability, notably showing higher rates of non-fatal outcomes in women.
  • While the overall cancer burden is rising, some specific cancers are declining, indicating that cancer control strategies are effective, highlighting the importance of ongoing prevention and awareness efforts, including HPV vaccination and cancer screenings.
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This systematic review aims to address the research gap in the performance of computational algorithms for the digital image analysis of HER2 images in clinical settings. While numerous studies have explored various aspects of these algorithms, there is a lack of comprehensive evaluation regarding their effectiveness in real-world clinical applications. We conducted a search of the Web of Science and PubMed databases for studies published from 31 December 2013 to 30 June 2024, focusing on performance effectiveness and components such as dataset size, diversity and source, ground truth, annotation, and validation methods.

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Cervical cancer (CC) continues to be a significant global health issue, which in part can be attributed to disparities in access to CC screening services. This study aims to conduct a trend of CC in Kazakhstan and to compare attitudes towards the screening program between women living in urban and rural areas. In the first stage, we conducted a trend study of CC indicators in Kazakhstan using official statistics.

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Objective: Globally, cervical cancer (CC) incidence is higher in rural areas than in urban areas that could be explained by the influence of many factors, including inequity in accessibility of the CC prevention measures. This review aimed to identify and analyze factors associated with a lack of cervical cancer screening and HPV vaccination programs in people living in rural areas and to outline strategies to mitigate these factors.

Methods: The literature search encompassed two focal domains: cervical cancer screening and HPV vaccination among populations residing in rural areas, covering publications between January 1, 2004 to December 31, 2021 in the PubMed, Google Scholar, Scopus, and Cyberleninka databases, available in both English and Russian languages.

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Introduction: Human papillomavirus (HPV) is a prevalent sexually transmitted infection linked to certain types of malignant neoplasms, notably cervical cancer (CC). In Kazakhstan, a high prevalence of high oncogenic HPV types (HR-HPV) has been observed, and CC ranks as the second most common malignancy among women with a crude incidence rate of 18.3 cases per 100 000 women.

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