Publications by authors named "Fatima Hoosen"

Introduction: We codesigned an intervention with a low-resourced community with the aim to investigate the effects of time-restricted eating (TRE) on changes in body weight and associated cardiometabolic outcomes in South African women living with overweight/obesity and HIV who have initiated dolutegravir (DTG)-based antiretroviral therapy (ART).

Methods And Analysis: Women with overweight or obesity (body mass index ≥25 kg/m², no upper limit), aged 20-45 years, living with HIV and in a low-resourced community, and receiving DTG-based ART for less than 2 years will be recruited from a community healthcare centre in Khayelitsha, Cape Town (n=152). Participants will be randomised 1:1 to the TRE group (n=76) or standard of care control group (n=76) for 12 months.

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Article Synopsis
  • The study investigates the feasibility of a time-restricted eating (TRE) intervention for women aged 20-45 living with both HIV and overweight/obesity in Cape Town, South Africa, to combat the weight gain associated with anti-retroviral treatment, specifically dolutegravir (DTG).
  • Factors influencing the adoption of TRE were identified, including psychological capability, social influences, and reflective motivation, utilizing models like the Capability, Opportunity, Motivation - Behaviour framework and Theoretical Domains Framework through interviews and a pilot trial.
  • In a 4-week pilot trial with 12 participants, retention was 100%, and positive outcomes included improved energy levels, appetite control, and weight loss, indicating that TRE was seen as an acceptable
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Given the high prevalence of overweight and obesity amongst educators, this study investigated the feasibility of the 16-week Health4LIFE weight loss intervention for primary school educators living with overweight/obesity in low-income settings in Cape Town, South Africa. The research comprised two sub-studies, a pilot randomised controlled trial testing the intervention (10 intervention, = 79 and 10 control schools, = 58), and an investigation of the perceptions of participating educators and principals. Feasibility outcomes included reach, applicability, acceptability, implementation integrity, and a hypothesis-generating signal of effect on lifestyle factors and weight.

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