Publications by authors named "Fatima Gomez"

Article Synopsis
  • RPE65 retinol isomerase is essential for vision by facilitating the visual cycle in the retina, but how it interacts with membranes remains unclear.
  • Recent studies reveal that specific amino acid residues (107-125) in RPE65 can change structure upon binding to membranes, transitioning from a flexible loop to an α-helical form, especially when palmitoylated at C112.
  • The α-helical structure enhances RPE65's ability to associate with membranes and perform its isomerization function, suggesting that palmitoylation plays a crucial role in its membrane recognition and binding.
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Background: Finite element analysis was used to compare fixation methods for double pelvic osteotomy (DPO). Using 3D scanning a stereolithography (stl) image was produced of a canine pelvis and this was subsequently refined in computer aided design (CAD). Using the CAD files, the images were imported in MSC Marc software to produce a working finite element (FE) model with 3 dimensional tetrahedral elements with linear shaped functions.

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The kinematic behavior of models that are based on the finite element method (FEM) for modeling the human body depends greatly on an accurate estimate of the parameters that define such models. This task is complex, and any small difference between the actual biomaterial model and the simulation model based on FEM can be amplified enormously in the presence of nonlinearities. The current paper attempts to demonstrate how a combination of the FEM and the MRS methods with desirability functions can be used to obtain the material parameters that are most appropriate for use in defining the behavior of Finite Element (FE) models of the healthy human lumbar intervertebral disc (IVD).

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