The hybrid material created by combining cellulose and MOF is highly promising and possesses a wide range of useful properties. Cellulose-based metal-organic frameworks (CelloMOFs) combine the inherent biocompatibility and sustainability of cellulose with the tunable porosity and diverse metal coordination chemistry of MOFs. Cellulose-MOF hybrids have countless applications in various fields, such as energy storage, water treatment, air filtration, gas adsorption, catalysis, and biomedicine.
View Article and Find Full Text PDFPlatelet-producing megakaryocytes (MKs) primarily reside in the bone marrow, where they duplicate their DNA content with each cell cycle resulting in polyploid cells with an intricate demarcation membrane system. While key elements of the cytoskeletal reorganizations during proplatelet formation have been identified, what initiates the release of platelets into vessel sinusoids remains largely elusive. Using a cell cycle indicator, we observed a unique phenomenon, during which amplified centrosomes in MKs underwent clustering following mitosis, closely followed by proplatelet formation, which exclusively occurred in G of interphase.
View Article and Find Full Text PDFMegakaryocytes (MK) undergo extensive cytoskeletal rearrangements as they give rise to platelets. While cortical microtubule sliding has been implicated in proplatelet formation, the role of the actin cytoskeleton in proplatelet elongation is less understood. It is assumed that actin filament reorganization is important for platelet generation given that mouse models with mutations in actin-associated proteins exhibit thrombocytopenia.
View Article and Find Full Text PDFBackground: COVID-19 pandemic has affected mankind globally. After the three waves since March 2020, the threat continues instilling fear in the minds. Vital parameter monitoring through remote health monitoring system (RHMS) becomes critical for effective disease management and manpower safety and confidence.
View Article and Find Full Text PDFCancer associated morbidity is mostly attributed to the dissemination of tumor cells from their primary niche into the circulation known as "metastasis". Mycobacterium indicus pranii (MIP) an approved immunotherapeutic agent against lung cancer (NSCLC) has shown potent anti-tumor activity in prior studies. While evaluating anti-tumor activity of MIP in mouse model, MIP treated animals typically exhibited less metastatic lesions in their pulmonary compartment.
View Article and Find Full Text PDFThe techniques and procedures involved in craniofacial distraction are constantly evolving. The understanding of histological and biochemical response at the distraction site is now improved. The cascade of events in distraction osteogenesis (DO) differs significantly from the typical fracture healing, and a better knowledge about these events has helped us identify suitable candidates for DO, make appropriate modifications to the distraction protocols and minimize the risk of complications.
View Article and Find Full Text PDFObjectives: To compare the effectiveness of metronidazole gel and mobile telephone short-message service (SMS) reminders on gingivitis in patients undergoing fixed orthodontic treatment.
Materials And Methods: The trial was double blinded (patient and investigator), and only the clinical trial unit pharmacist was unblinded. Data were collected from patients undergoing fixed orthodontic treatment for at least 6 months.
Objective: The present study was aimed to assess the effectiveness of antimicrobial gels along with conventional tooth brushing to improve gingival health in patients undergoing fixed orthodontic treatment.
Materials And Methods: All randomized and non-randomized clinical trials done on human subjects were explored in major health science databases (PubMed, CINAHL Plus, EBSCO Dent & Oral Sciences and Cochrane). An additional manual search was done on Google Scholar and on www.
Dental Press J Orthod
August 2019
Introduction: Resting tongue posture affects the surrounding structures and, theoretically, may result in altered arch form and jaw relationship.
Objective: The objective of the present study was to investigate the association between resting tongue posture as observed in lateral cephalometric radiograph, sagittal jaw relationship and arch form.
Methods: The study was conducted on pretreatment lateral cephalograms and dental casts of 90 subjects.
Introduction: To find the association between the morphological characteristics of palatal rugae and sagittal skeletal patterns.
Methods: The retrospective charts review was conducted at the Aga Khan University Hospital from April to June 2016, and comprised data obtained from the pretreatment dental cast of orthodontic patients visiting the dental clinics over 5 years from 2011 to 2015. The sample was divided equally in three malocclusion groups based on sagittal skeletal relationship Class I, Class II and Class III.
The face is the most expressive zone of the human body that communicates our feelings and thoughts. This may also influence the interaction between people. The aesthetic adjunctive procedures are life-changing.
View Article and Find Full Text PDFDental Press J Orthod
February 2020
Introduction: Palatal rugae complete its development during early intrauterine life, whereas dental malocclusions in permanent dentition establishes several years into the post-natal life.
Objective: The objective of present study was to determine if there is an association between the palatal rugae pattern and Angle's classes of malocclusion.
Methods: A cross-sectional study was conducted on pretreatment dental casts of 184 patients.
In the current era of expedited orthodontics, among many clinicians, tertiary care hospitals and patients, surgery first orthognathic approach (SFOA) has gained popularity. The advantages of SFOA (face first approach) are the reduced overall treatment duration and the early improvement in facial esthetics. In SFOA, the absence of a presurgical phase allows surgery to be performed first, followed by comprehensive orthodontic treatment to achieve the desired occlusion.
View Article and Find Full Text PDFIntroduction:: Differential diagnosis of skeletal and dental relationships is crucial for planning orthodontic treatment. Overbite depth indicator (ODI) and anteroposterior dysplasia indicator (APDI) had been introduced in the past for assessment of vertical and sagittal jaw relationships, respectively.
Objective:: The objectives of this study were to evaluate the reliability of ODI and APDI in overbite and Angle malocclusions, as well as assess their diagnostic reliability among males and females of different age groups.
Background: Intestinal parasitic infections (IPIs) are endemic worldwide and have been the cause of illness and disease worldwide.
Objectives: The study is aimed to estimate prevalence, intensity, and factors associated with IPIs among school children aged 6-12 years.
Materials And Methods: This cross-sectional survey was carried out from February to July 2010, in the diagnostic laboratory of Microbiology department.