Publications by authors named "Fatima Ezzohra Eddehbi"
[Clinical associations of anti-Jo1 antibodies in a Moroccan population].
Ann Biol Clin (Paris)
November 2024
Anti-Jo1 antibodies are usually known markers of myositis. However, they can be associated with different pathologies. We aimed to determine the immuno-clinical characteristics of patients with positive anti-Jo1.
View Article and Find Full Text PDFFrequency of the Main Human Leukocyte Antigen A, B, DR, and DQ Loci Known to Be Associated with the Clearance or Persistence of Hepatitis C Virus Infection in a Healthy Population from the Southern Region of Morocco: A Preliminary Study.
Diseases
May 2024
Article Synopsis
- Hepatitis C Virus (HCV) infection is a major global health issue influenced by the host's immune response, particularly through Human Leukocyte Antigen (HLA) molecules.
- A study in Morocco examined HLA A, B, DR, and DQ alleles in 703 healthy individuals to identify patterns associated with HCV clearance or persistence, finding distinct allele frequencies that align with known global trends.
- The findings emphasize the importance of genetic factors in HCV outcomes and suggest the need for further research, as well as the potential establishment of a national HLA data bank in Morocco.
Inborn errors of immunity (IEI) are characterized by diverse clinical manifestations that are dominated by atypical, recurrent, chronic, or severe infectious or non-infectious features, including autoimmunity, lymphoproliferative disease, granulomas, and/or malignancy, which contribute substantially to morbidity and mortality. Some data suggest a correlation between clinical manifestations of IEI and altered gut microbiota. Many IEI display microbial dysbiosis resulting from the proliferation of pro-inflammatory bacteria or a decrease in anti-inflammatory bacteria with variations in the composition and function of numerous microbiota.
View Article and Find Full Text PDFContext: Anti-double-stranded deoxyribonucleic acid antibodies (dsDNA Abs) are highly specific markers of systemic lupus erythematosus (SLE). Multiple methods are employed for their detection in routine diagnostics.
Objectives: The aim of this study was to evaluate a diagnostic approach for anti-dsDNA Abs using DNA-ELISA and fluorescence test (CLIFT), in combination with antinuclear antibody (ANA) screening.