Publications by authors named "Fatima Chilaca Rosas"

Article Synopsis
  • Head and neck squamous cell carcinomas (HNSCC) exhibit diverse features influenced by human papillomavirus (HPV) status, highlighting the need for careful patient stratification in Mexico.
  • A study analyzing 414 Mexican patients revealed that 32.3% tested positive for p16 and 22.3% for HPV, with HPV types 16, 18, and others being the most common.
  • High expression levels of certain genes were linked to poor survival rates, while others indicated better outcomes, and specific signaling pathways were found to be downregulated in HPV-positive cases, providing potential targets for therapy.
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Male pseudohermaphroditism and androgen insensitivity syndrome cases have an increased risk of developing testicular cancer due to many factors such as mutations, hormonal disturbances involving gonadotropins and cryptorchidism. We describe the clinical features, diagnosis and treatment of two cases with partial androgen insensitivity syndrome and testicular cancer development, which were handled at the National Cancer Institute of Mexico.

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We present 4 case studies of patients with Down's syndrome and testicular germ-cell cancer, treated with conventional methods at the National Cancer Institute of Mexico, with similar outcomes as patients without this syndrome. There are several reports of testicular cancer arising in patients with Down's syndrome worldwide, mainly from Caucasian populations. We discuss some theories about the association and the possible increase of incidence.

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