Publications by authors named "Fatima Al-Rostum"
Article Synopsis
- Different somatic cell types, especially fibroblasts, are commonly used in nuclear transfer experiments for cloning, but their effectiveness can vary based on their origin and culture conditions.
- Previous studies have shown blastocyst rates from these experiments can be as high as 45%, prompting further investigation into why different fibroblast lines yield different developmental outcomes.
- Findings suggest that the specific fibroblast line has a greater impact on embryo development than factors like passage number, indicating epigenetic variations in gene expression may play a crucial role in nuclear donor cell performance.
