Toxicological analyses of the venoms of Nigerian vipers Echis ocellatus and Bitis arietans.

Background: Among the medically important snakes in Nigeria, Echis ocellatus and Bitis arietans have the most lethal venom. These venoms were classified according to the presence of snake venom metalloproteinases (SVMPs), snake venom phospholipase A (PLAs), and snake venom serine proteases (SVSPs). Toxicological analyzes were performed to understand the significance of different protein families in venoms.

lowered serum carcinoembryonic antigen and antigen 125 in 7,12-Dimethylbenz[]anthracene-induced Mammary Carcinogenesis in Female Albino Rats.

Aim: This study is aimed at evaluating the anticancer effect of the aqueous extract of (L.) Sw in 7,12-Dimethlbenz[]anthracene (DMBA) - induced mammary cancer.

Methods: Tumors were induced via a single intraperitoneal injection of DMBA (dissolved in olive oil) at a dose of 80 mg/kg body weight to the test rats and allowed to develop for about four months.