Viscoelastic Behavior of Drug-Loaded Polyurethane.

Drug-eluting stents are desirable platforms for local medicine delivery. However, the incorporation of drugs into polymers can influence the mechanical and physicochemical properties of said matrix, which is a topic that is still poorly understood. In fact, this is more noticeable since the apposition is most often accompanied by mechanical stresses on the polymer coating, which can induce therapeutic failure that can result in death.

Critical evaluation of three hemodynamic models for the numerical simulation of intra-stent flows.

We evaluate here three hemodynamic models used for the numerical simulation of bare and stented artery flows. We focus on two flow features responsible for intra-stent restenosis: the wall shear stress and the re-circulation lengths around a stent. The studied models are the Poiseuille profile, the simplified pulsatile profile and the complete pulsatile profile based on the analysis of Womersley.