Calcium phosphate mineralizing peptides are of special importance for dental and orthopedic applications, such as caries remineralization and improved osteointegration. Uncovering the mechanism of action for such peptides is an ongoing challenge with the aim of a better fundamental understanding of biomineralization processes and developing optimized peptides for clinical use. It has recently been reported that "adjacent oppositely charged residue" motifs are found abundantly in cation binding, inorganic surface binding, or biomineralization-related proteins and may play a key role in the biomineralization events.
View Article and Find Full Text PDFJ Mech Behav Biomed Mater
January 2021
Bonding with dentin is a complex process involving physical and chemical adhesion where the adhesive must be able to penetrate and envelop collagen fibers. Acid etching clears the dentin of debris, which prevents adhesives to interact with dentin. However, it also demineralizes the outermost surface of dentin and exposes collagen fibers.
View Article and Find Full Text PDFThe aim of the present study was to investigate in the fractal dimension (FD) time-dependent changes of periapical bone after two different apexification treatments in teeth with immature apices and apical periodontitis. This study included 55 cases treated with apexification. Cases were divided into two groups: a calcium hydroxide group and a mineral trioxide aggregate group.
View Article and Find Full Text PDFUnlabelled: Mineralization-promoting peptides are attractive candidates for new remineralization systems. In previous studies, peptides have been applied as aqueous solutions, which is not a clinically relevant form.
Objective: This study aims to investigate the efficiency of a mineralization-promoting peptide, applied in varnish, on remineralizing artificial caries on primary teeth.
Aims And Objectives: The aim of this study was to compare the efficacy of different remineralization (RM) agents on RM of artificial caries by evaluating the density, light reflection, and the crystal size of the newly formed mineral in primary and permanent teeth.
Materials And Methods: Caries-free primary and permanent molars were divided into seven groups ( = 20) and treated with: G1 - Deionized water, G2 - Colgate Cavity Protection, G3 - Sensodyne Rapid Relief, G4 - GC MI Paste Plus, G5 - Clinpro Tooth Creme, G6 - Clinpro 5000, and G7 - Sensodyne Repair and Protect. Lesion depths were evaluated using laser fluorescence (DIAGNOdent), and polarized light microscopy (PLM), and the minerals were evaluated using X-ray diffractometry (XRD).
The aim of the present study was to evaluate and compare the effect of acidetching and Er, Cr:YSGG laser treatment before the reattachment of incisal fragments in coronal fractures of permanent incisor teeth. Sixty-six sound human maxillary incisors were randomly divided into 3 groups (n=22). Teeth were embedded in self-cure acrylic resins by leaving one-third of the crowns out, and uncomplicated crown fractures were obtained using an Instron testing device.
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