Dual-source computed tomography may define cardiac contusion in patients with blunt chest trauma in ED.

We report a 20-year-old woman with blunt chest trauma because of a motor vehicle injury who has traumatic asphyxia and hypotension. The diagnosis of blunt cardiac injury was put by using dual-energy computed tomography in the emergency department because other laboratory and imaging modalities were useless. After hospitalization in intensive care unit, she was treated with supportive and antiedema therapy.

Investigation of the functional single-nucleotide polymorphisms in the transporter and susceptibility to colorectal cancer.

Breast cancer resistance protein () protects tissues by actively transporting xenobiotics and their metabolites out of the cells. is expressed in the apical membrane of normal intestinal and colonic epithelium. The substrates include a number of structurally unrelated compounds, such as drugs, pesticides, carcinogens and endogenous compounds.

Influence of the functional polymorphisms in the organic anion transporting polypeptide 1B1 in the susceptibility to colorectal cancer.

Colorectal cancer is an important cause of death throughout the world, and its etiology involves the interaction of genetic and environmental factors. Transporter proteins are important in protecting organs from xenobiotics or toxins. Organic anion-transporting polypeptide 1B1 (OATP1B1) plays role in hepatic uptake and clearance of albumin-bound amphipathic organic compounds, including endogen substances, drugs, or xenobiotics.

Associations between the functional polymorphisms in the ABCB1 transporter gene and colorectal cancer risk: a case-control study in Turkish population.

Colorectal cancer is among the most common cancer types in the world and its etiology involves the interaction of genetic and environmental factors. ABCB1 is highly expressed in the apical surface of colonic epithelial cells and acts as an efflux pump by transporting toxic endogenous substances, drugs and xenobiotics out of cells. ABCB1 polymorphisms may either change its protein expression or alter its function.