Antimicrobial evaluation of (Boiss. & Heldr.) E. Hossain extracts using and model against urinary system pathogens.

(Boiss. & Heldr.) E.

Chemical profile, pharmacological activity and Ten. evaluation of essential oil based on distillation time.

The medicinal plant Ten. was widely utilized as spice, tea and traditional medicine. The objective of the current study was to examine the chemical composition and biological activities (LOX, MMP-1, and MMP-12 enzyme inhibition activity and cytotoxicity on A549 cell line) of extracts and essential oils.

Biological Activities of the Fruit Essential Oil, Fruit, and Root Extracts of Korovin, the Putative Anatolian Ecotype of the Silphion Plant.

In the present study, preliminary phytochemical investigations were performed on the fruit essential oil and antioxidant-rich methanolic extracts of the fruits and roots of , the putative Anatolian ecotype of the Silphion plant, to corroborate its medicinal plant potential and identify its unique characteristics amongst other species. The essential oil from the fruits of the endemic species collected from Aksaray was analyzed by GC and GC/MS. The main components of the oil were determined as shyobunone (44.

Protective effects of Rubus tereticaulis leaves ethanol extract on rats with ulcerative colitis and bio-guided isolation of its active compounds: A combined in silico, in vitro and in vivo study.

The aim of this study was to evaluate the therapeutic effect of active ethanol extract obtained from the leaves of Rubus tereticaulis (RTME) against colitis, and to purify major compounds from this extract by bioassay-directed isolation. Rats with colitis induced via intra-rectal acetic acid administration (5%, v/v) received RTME or sulfasalazine for three consecutive days. On day four, all rats were decapitated, and the colonic tissue samples were collected for macroscopic score, colon weight, reduced glutathione (GSH), myeloperoxidase (MPO), and malondialdehyde (MDA) analyses.

Comparative Studies on Essential Oil and Phenolic Content with In Vitro Antioxidant, Anticholinesterase, Antimicrobial Activities of Afan. and subsp. Afan. L. Growing in Eastern Turkey.

The potential applications of species in various industries have encouraged the examination of their phytochemical components along with their biological potential. In the present study, phenolic contents and essential oil compositions together with the in vitro biological activities of the aerial parts from Afan. and subsp.

Phytochemical profile, antioxidant, antiproliferative, and enzyme inhibition-docking analyses of Celep & Doğan.

Celep & Doğan is an endemic species of Turkey. To our knowledge, the number of studies on biological activities and phytochemical profiling of this plant is quite limited. Therefore, this study aimed to analyze its activities and phytochemical content in detail.

New bone-generative effect of Salvia officinalis L. in the expanded midpalatal suture : An in vivo and in vitro study.

Purpose: The aims of this study were to evaluate the effects of systemic administration of Salvia officinalis Linnaeus (L.) leaf extract on new bone formation in the expanded premaxillary suture in rats in vivo and to examine the antioxidant effects and phenolic profile of Salvia officinalis (SO) leaf and root extracts in vitro.

Methods: Fourteen male Sprague Dawley rats were allocated to two groups: SO group (n = 7) and control group (n = 7).

Phytochemical composition and pharmacological activities of L. collected from eastern Turkey.

species that belong to the family Lamiaceae have been traditionally used for their medicinal properties. is one the most widespread members of the genus for its use in the treatment of several diseases. In this study, the essential oil and phenolic composition of the aerial parts from were assessed by GC-FID, GC/MS, and LC-MS/MS as well as for its total phenolic content.

Phytochemical Characterization of Phenolic Compounds by LC-MS/MS and Biological Activities of L., (L.) Schreber and L. from Turkey.

Objectives: In this study, it was aimed to characterize the phenolic contents of L., (L.) Schreber and L.

Phytochemical characterisation of Phlomis linearis Boiss. & Bal and screening for anticholinesterase, antiamylase, antimicrobial, and cytotoxic properties.

In the present work, essential oil and fatty acids and extracts obtained from aerial parts of  Boiss. & Bal. were investigated for chemical composition and biological activities.

biological activity of Mill. infusion against amyloid -peptide-induced toxicity and inhibition of GSK-3, CK-1, and BACE-1 enzymes relevant to Alzheimer's disease.

species have been traditionally used to improve cognition and have been proved to be a potential natural treatment for Alzheimer's disease. Mill. (Turkish sage or Greek sage) demonstrated to have anticholinergic effects .

Assessment of (L.) J. Gay for phytochemical composition and antioxidant, anti-inflammatory, antidiabetic and antimicrobial activities.

Phytochemical profiles of essential oil (), fatty acids, and -hexane (CAH), diethyl ether (CAD), ethyl acetate (CAE) and methanol extracts (CAM) of L. J. Gay (syn.

Chemical composition and antioxidant, cytotoxic, and insecticidal potential of Valeriana alliariifolia in Turkey.

Valeriana is a common plant species used for various healing purposes in folk medicine since antiquity. This study investigates the phytochemical profile, antioxidant, cytotoxic, and insecticidal activity of Valeriana alliariifolia Adams, a species that has traditionally been used in Turkey. For the analyses we prepared four root extracts of V.

Potential Antioxidant and Enzyme Inhibitory Effects of Nanoliposomal Formulation Prepared from Rech. f. Extract.

Rech. f. is a species that grows only in Hatay, Turkey and is used as a traditional stomachic tea.

Assessment of selected Saudi and Yemeni plants for mosquitocidal activities against the yellow fever mosquito .

As part of our continuing investigation for interesting biological activities of native medicinal plants, thirty-nine plants, obtained from diverse areas in Saudi Arabia and Yemen, were screened for insecticidal activity against yellow fever mosquito (L.). Out of the 57 organic extracts, , and exhibited over 80% mortality against adult female at 5 μg/mosquito.

Solanum vegetable-based diets improve impairments in memory, redox imbalance, and altered critical enzyme activities in Drosophila melanogaster model of neurodegeneration.

The effects of two Solanum vegetables, S. macrocarpon L. (African eggplant), and S.

Two Acylated Isoscutellarein Glucosides with Anti-Inflammatory and Antioxidant Activities Isolated from Endemic Stachys Subnuda Montbret & Aucher ex Benth.

In this study, we report anti-inflammatory and antioxidant activities of two acylated isoscutellarein glucosides isolated from ethyl acetate extract of Stachys subnuda aerial part. 4'-O-methylisoscutellarein-7-O-2''-O-(6∙∙∙-O-acetyl-β-D-allopyranosyl)-β-D-glucopyranoside (SS1) and isoscutellarein-7-O-2''-O-(6∙∙∙-O-acetyl-β-D-allopyranosyl)-β-D-glucopyranoside (SS2) were isolated as major compounds from ethyl acetate extract (SSEA). Also, 2 hydroxycinnamic acid derivatives, and 5 isoscutellarein glucoside derivatives in the SSEA were identified using LC-MS/MS.

Effect of Horse-chestnut seed extract on matrix metalloproteinase-1 and -9 during diabetic wound healing.

The effects of aqueous-ethanol extract of Horse chestnut (HCE) on MMP-1 and MMP-9 expressions during cutaneous wound healing in diabetic rats were investigated in this study. The expressions of MMP-1 and MMP-9, wound closure, myeloperoxidase (MPO) activity, hydroxyproline, and malondialdehyde (MDA) levels in wound tissue were measured. Quercetin glucuronide in HCE was identified as main compound using a LC-MS/MS.

Furanocoumarin Content, Antioxidant Activity, and Inhibitory Potential of Heracleum verticillatum, Heracleum sibiricum, Heracleum angustisectum, and Heracleum ternatum Extracts against Enzymes Involved in Alzheimer's Disease and Type II Diabetes.

Hexane extracts of Heracleum verticillatum, H. sibiricum, H. angustisectum, and H.

Antibacterial, anticandidal and antioxidant properties of Tanacetum argenteum (Lam.) Willd. subsp. flabellifolium (Boiss. & Heldr.) Grierson.

In the present study hydrodistilled essential oil and total methanol extracts of Tanacetum argenteum subsp. flabellifolium have been evaluated for their antimicrobial and antioxidant effects. The chemical composition of the oil and the crude extract were determined by GC/FID, GC/MS and LC/DAD/ESI-MS systems respectively.

Chemical composition and biological investigation of Pelargonium endlicherianum root extracts.

Context: Pelargonium endlicherianum Fenzl. (Geraniaceae) roots and flowers are traditionally used in Turkey as a decoction treatment against intestinal parasites. Neither the chemical composition nor the potential bioactivity of the plant roots has been studied before.

The LC/ESI-MSMS Profiles and Biological Potentials of Vitex agnus castus Extracts.

The chemical profile, cytotoxic and apoptotic effect, and antioxidant activity were determined of ethanolic extracts of Vitex agnus-castus L. (chaste tree). Ripened fruits and fruitless aerial parts were extracted with ethanol, and the chemical characterization of the extracts was determined by LC/ESI-MS-MS.

Chemical Composition and Biological Activity of Centaurea baseri: New Species from Turkey.

The genus Centaurea L. is one of the largest and important genera of Asteraceae family. Centaurea species have been widely used as herbal remedies in folk medicine for their antidandruff, antidiarrheic, antirheumatic, anti-inflammatory, choleretic, diuretic, digestive, stomachic, astringent, antipyretic, cytotoxic, and antibacterial properties.

In vitro antioxidant properties and anthocyanin compositions of elderberry extracts.

In this study, dried elderberry fruits growing wild in Turkey were macerated using different solvents and an infusion was prepared according to traditional methods. All extracts were investigated for their total phenolic content, total monomeric anthocyanins, qualitative-quantitative determination of cyanidin-3-glucoside (by HPLC-UV analysis), anthocyanin compositions (by LC/MS-MS), free radical scavenging activity (DPPH and ABTS) and inhibition of β-carotene/linoleic acid co-oxidation. An extract with 70% ethanol was found to be richer in cyanidin-3-glucoside when compared to the other extracts.