This study aims to compare two different single-puncture arthrocentesis (SPA) Type 2 techniques, the Y-shaped cannula and the concentric needle methods, in terms of intraoperative parameters. In the study, data from 32 unilateral temporomandibular joint (TMJ) arthrocentesis procedures, including procedure duration (seconds), the number of cannula relocations, and procedural difficulty (evaluated using a visual analog scale), were retrospectively analyzed. The Y-shaped cannula technique was found to significantly reduce procedure duration (284.
View Article and Find Full Text PDFIn this study, we investigated the combined treatment of 5-fluorouracil (5-FU) and Anatolian propolis extract (PE) on colorectal cancer (CRC)using in vitro and in vivo studies. We exposed luciferase-transfected (Lovo-Luc CRC) cells and healthy colon cells (CCD-18Co) to varying concentrations of 5-FU and PE to assess their genotoxic, apoptotic, and cytotoxic effects, as well as their intracellular reactive oxygen species (iROS) levels. We also developed a xenograft model in nude mice and evaluated the anti-tumor effects of PE and 5-FU using various methods.
View Article and Find Full Text PDFCutaneo us vasculitis (CV) has a broad spectrum of etiologies, and drugs are one of the main culprits. With the increasing use of targeted therapies in medicine, especially in rheumatology and oncology, the number of CV cases reported due to these drugs has increased. Therefore, the recognition and treatment of CV associated with targeted agents have become more and more important.
View Article and Find Full Text PDFCerebellar ataxia, neuropathy, vestibular areflexia syndrome (CANVAS) is a late-onset, slowly progressive disorder characterized by cerebellar ataxia, sensory neuropathy and bilateral vestibulopathy. Recently, a biallelic intronic AAGGG repeat expansion, (AAGGG), in the Replication Factor C1 (RFC1) gene was identified as the cause of this disorder. In this study, we describe the phenotypic features of five patients from five different families diagnosed as CANVAS.
View Article and Find Full Text PDFObjective: To assess outcomes of Syrian refugees undergoing coronary artery bypass surgery in a tertiary hospital in Turkey.
Methods: We sought for in-hospital mortality and one year all-cause mortality as the main outcomes. We reviewed records of 67 Syrian and 427 Turkish patients undergoing isolated coronary bypass surgery between 2015 January and 2017 January retrospectively.
[Purpose] To investigate the effect of vitamin D supplementation on rehabilitation outcomes and balance in patients having hemiplegia due to ischemic stroke. [Subjects and Methods] Vitamin D levels of 132 patients hospitalized for hemiplegia rehabilitation due to ischemic stroke were tested. Consequently, 86/132 patients had low vitamin D levels, 72 of which met the inclusion criteria and were included in the study.
View Article and Find Full Text PDFThe aim of this study was to search for the frequency of late onset Pompe disease (LOPD) among patients who had a myopathy with unknown diagnosis registered in the pre-diagnostic part of a novel registry for LOPD within a collaborative study of neurologists working throughout Turkey. Included in the study were 350 patients older than 18 years who have a myopathic syndrome without a proven diagnosis by serum creatine kinase (CK) levels, electrodiagnostic studies, and/or muscle pathology, and/or genetic tests for myopathies other than LOPD. Acid alpha glucosidase (GAA) in dried blood spot was measured in each patient at two different university laboratories.
View Article and Find Full Text PDFStudy Design: Psychometrics study.
Objectives: To assess the reliability of the Modified Ashworth Scale (MAS) and Modified Tardieu Scale (MTS) in patients with spinal cord injuries (SCIs).
Setting: Inpatient rehabilitation clinics at two state hospitals.
Recently, protein purification methods have a very wide area of research. Many of these methods are both expensive and multi-stage methods, that are needed in specific equipment. In this study, biopolymer coated magnetic nanoparticles, carboxymethyl cellulose (CMC) and chitosan (CH) coated FeO (magnetite) nanocomposites, are used in a new purification process.
View Article and Find Full Text PDFFamilial Mediterranean fever (FMF) is an autosomal recessive autoinflammatory disease of childhood and adulthood. Development of systemic amyloidosis and frequent attack influence quality of life and survival. There is sporadic evidence indicating subclinical inflammation in patients with FMF.
View Article and Find Full Text PDFIn this work, super paramagnetic magnetite nanoparticles were synthesized onto/into zeolite, then loaded with anti-cancer drug 5-fluorouracil (5-FU). The physical properties of the prepared nanocomposite and drug loaded nanocomposite were characterized using different techniques. The drug loading and releasing behavior of the magnetic nanocarrier was investigated and the drug-loaded nanoparticles exhibited a sustained release of drug without any burst release phenomenon.
View Article and Find Full Text PDFMater Sci Eng C Mater Biol Appl
January 2016
their effects on the properties of these biosensors. Biosensors were prepared by Horseradish peroxidase (HRP) immobilization on the composite electrodes composed of carbon black, carbon nanofiber (CNF), extended graphite, multiwalled carbon nanotube (MWCNT), reduced graphene oxide (REGO) and poly(glycidyl methacrylateco-vinylferrocene) (P(GMA-co-VFc)) as mediator, covalent linker, and host matrix for carbon derivatives. The modified pencil graphite electrode (PGE) was used for the detection of hydrogen peroxide and to follow electrochemical behavior of different carbon derivatives which were recorded.
View Article and Find Full Text PDFPurpose: To evaluate the effect of N-acetylcysteine on selenite-induced cataract formation in a rat model.
Materials And Methods: Thirty-four Sprague-Dawley rat pups were divided into three groups. Eight pups received only selenite on postpartum day 10 (group 1), 14 pups received selenite on day 10 and additional acetylcysteine on postnatal days 9 to 15 (group 2), and 12 pups received only saline (group 3, control).
Purpose: To compare optic disc measurements achieved by slit-lamp funduscopy, Heidelberg Retina Tomography II (HRT II), and stereoscopic optic nerve photos (SONP) in glaucomatous, ocular hypertensive, and normal eyes.
Methods: A total of 176 eyes (glaucomatous [n=87], ocular hypertensive [n=40], and normal eyes [n=49]) of 90 participants were studied. Each participant underwent a full ophthalmic examination, including automated perimetry, slit-lamp funduscopy, HRT II, and SONP.
Aim: The aim of this study is to evaluate the effect of erythropoietin and hemodialysis (HD) on serum Endotheli-1 (ET-1) and intraocular pressure (IOP) levels in HD patients.
Methods: The study group was composed of 34 chronic HD patients undergoing erythropoietin (EPO) treatment, while the control group was composed of 16 chronic HD patients without EPO treatment. Serum samples for measuring levels of ET-1 were taken 1 h before and after HD.
Background: The purpose of the study was to assess refractive errors and ocular abnormalities in intellectually disabled (ID) children and adults.
Methods: In this study, a random sample of 180 participants with ages ranging from 9 to 50 were recruited and examined between January and April 2006. Refractive errors were measured by photorefractometer.
Purpose: To compare the results of photorefraction measurement obtained with a Plusoptix CR03 to those of cycloplegic retinoscopy as a standard refraction method in children.
Methods: We assessed the refractive status of 204 eyes in 204 healthy children. The values acquired via photorefraction (noncycloplegic refraction) with a Plusoptix CR03 device were compared with those obtained via cycloplegic retinoscopy.
Purpose: To determine the concentration of hydroxyproline (Hyp) in aqueous humor and serum samples of patients with and without pseudoexfoliation (PEX).
Patients And Methods: Aqueous humor and serum Hyp levels were measured in cataract patients. Patients were divided into PEX and control groups.
Purpose: To assess central corneal thickness (CCT) values in individuals with intellectual disabilities (ID).
Methods: The study group was made up of 25 participants with ID (mean age, 36.9 +/- 8.
Purpose: To evaluate effects of melatonin on sodium selenite-induced cataract formation.
Methods: Twenty-three Sprague-Dawley rat pups were randomized into three groups. Group 1(n = 9), injected with selenite (s.