Publications by authors named "Fathy M El-Fasakhany"
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Synopsis of recent research by authors named "Fathy M El-Fasakhany"
Fathy M El-Fasakhany's research primarily focuses on the enzymatic processes involving N-acetylglucosamine 6-O-sulfotransferases (GlcNAc6STs), emphasizing their role in the synthesis of L-selectin ligands which are crucial for lymphocyte homing.
His studies explore the specificity and functional significance of different GlcNAc6ST isoforms, revealing their distinct substrate preferences and implications in various biological contexts, including tumor biology.
Additionally, El-Fasakhany has investigated the role of chondroitin 6-sulfotransferase (C6ST) in brain development and lymphocyte populations, using gene knockout models to elucidate its physiological importance in vivo.