Publications by authors named "Fatena Bellahcene"
Article Synopsis
- IMGT is an international information system created in 1989 to standardize and manage immunogenetics data, founded by Marie-Paule Lefranc in France.
- It serves as a comprehensive resource for immunoglobulins, T cell receptors, and immune system proteins, providing access to standardized information across genomics, proteomics, and 3D structures.
- IMGT supports various research fields, including medical and veterinary studies, biotechnology, and diagnostics, and is freely available online.
Background: Adaptative immune repertoire diversity in vertebrate species is generated by recombination of variable (V), diversity (D) and joining (J) genes in the immunoglobulin (IG) loci of B lymphocytes and in the T cell receptor (TR) loci of T lymphocytes. These V-J and V-D-J gene rearrangements at the DNA level involve recombination signal sequences (RSS). Whereas many data exist, they are scattered in non specialized resources with different nomenclatures (eg.
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