Publications by authors named "Faten Sid Idris"
Article Synopsis
- - Atopic dermatitis (AD), commonly known as eczema, is a widespread and itchy inflammatory skin condition, particularly prevalent in children, especially in affluent countries; only a small percentage of cases continue into adulthood and can be severe.
- - The condition is influenced by immune system responses, genetics (like filaggrin gene mutations), and environmental factors, leading to a compromised skin barrier and a heightened immune response.
- - This review focuses on the complexities pediatricians face in treating AD and highlights the various treatment options available, aiming to improve care and quality of life for affected children and their families.
Article Synopsis
- * This review examines the effectiveness of glucagon-like peptide-1 (GLP-1) receptor agonists in aiding weight loss, following PRISMA guidelines and analyzing relevant studies from the past 5-10 years.
- * Out of 698 studies, 10 were included, demonstrating that GLP-1 agents can help reduce body weight and may also provide heart protection, suggesting potential for use in clinical obesity treatments.
Article Synopsis
- - Congenital torticollis is when a newborn's neck tilts abnormally, often due to issues with the sternocleidomastoid muscle, leading the chin to point away from the affected side.
- - Other causes of congenital torticollis can include cervical vertebrae anomalies, syndromes, and ocular defects, which require thorough diagnostic imaging to identify.
- - Misdiagnosis is common, as illustrated by a case where a child treated for congenital muscular torticollis for a year actually had cervical vertebrae malformations, highlighting potential financial and psychosocial impacts.
Article Synopsis
- - Neuropeptide CGRP plays a crucial role in migraines, and CGRP monoclonal antibodies (erenumab, galcanezumab, fremanezumab, and eptinezumab) are FDA-approved medications that have shown promising results in migraine prevention.
- - A systematic review was conducted to evaluate the effectiveness and safety of these CGRP antibodies, revealing them to be effective and safe, possibly serving as a first-line treatment for migraines.
- - The study suggests that combining CGRP antibodies with onabotulinumtoxinA may further enhance migraine prevention and highlights the need for more research to explore individual patient characteristics that affect treatment outcomes.
Article Synopsis
- A significant number of kids are impacted by allergy diseases, prompting concerns about public health globally.
- The study aims to explore whether a mother's diet during pregnancy and breastfeeding affects the likelihood of children developing allergies, particularly food allergies and eczema.
- By reviewing literature from 2019 to 2022, the researchers seek to identify dietary factors that may help prevent allergies, aiming to improve health outcomes for allergic children and their families.
Article Synopsis
- Immune checkpoint inhibitors, especially PD-1 and PD-L1 inhibitors, have transformed cancer treatment by using the immune system to fight tumors.
- PD-L1 is a protein that suppresses the immune response when it interacts with PD-1 receptors on T-cells, leading to increased cancer cell survival.
- Clinical trials show that PD-1/PD-L1 inhibitors are effective against various advanced cancers, but challenges like resistance and side effects require ongoing research and combination therapies for better outcomes.
Article Synopsis
- * The systematic review analyzed 19 studies, including randomized trials and observational data, to assess how SGLT2 inhibitors might reduce heart-related issues like heart attacks and strokes.
- * While the findings suggest that SGLT2 inhibitors could significantly lower cardiovascular risks, the study had limitations, such as excluding older research and being restricted to English-language articles.
Article Synopsis
- The exact cause of inflammatory bowel disease (IBD) is unclear, but both environmental and genetic factors are believed to play a role, with exclusive enteral nutrition (EEN) showing promise for Crohn's disease but not yet being a first-line treatment.
- Dietary modifications, particularly increasing anti-inflammatory foods and reducing foods high in inflammatory compounds, have been linked to improvements in patients with ulcerative colitis in remission.
- Various diet alternatives have been explored in IBD treatment, with no significant differences between EEN and partial enteral nutrition, while strict diets like the specific carbohydrate diet (SCD) and Mediterranean diet (MD) show positive outcomes, highlighting the need for further research on effective dietary interventions.
