Publications by authors named "Faten Arouri"
Background: Dihydropyrimidine dehydrogenase (DPD) is a key enzyme in the metabolism of fluoropyrimidines. Variations in the encoding DPYD gene are associated with severe fluoropyrimidine toxicity and up-front dose reductions are recommended. We conducted a retrospective study to evaluate the impact of implementing DPYD variant testing for patients with gastrointestinal cancers in routine clinical practice in a high volume cancer centre in London, United Kingdom.
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- The study analyzed 34 patients with complex proximal humerus fractures treated with long contoured locking plates; 25 patients' outcomes were evaluated after a mean follow-up of 27 months.
- Pain levels were relatively low at the final follow-up, with an average VAS score of 3.6 and minimal severe pain reported.
- Despite some complications, including infections and non-unions in a few cases, the findings suggest that long contoured locking plates are an effective treatment method for these types of fractures.