Publications by authors named "Faten A Mahmoud"

Article Synopsis
  • Diabetic patients often suffer from low saliva production, leading to difficulties with eating, swallowing, and an increased risk of gum disease.
  • This study tested whether agmatine could enhance salivation in diabetic rats made hyposalivatory through a substance called streptozotocin (STZ).
  • Results showed that agmatine improved salivary gland function and reduced the negative effects of diabetes on these glands, suggesting it may help manage hyposalivation.
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Status epilepticus (SE), the most severe form of epilepsy, leads to brain damage. Uncertainty persists about the mechanisms that lead to the pathophysiology of epilepsy and the death of neurons. Overloading of intracellular iron ions has recently been identified as the cause of a newly recognized form of controlled cell death called ferroptosis.

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Folic acid (FA), with its anti-inflammatory and antioxidant properties, may offer protection against ischemia-reperfusion (IR) injury. This study investigated whether FA safeguards rat kidneys from IR by targeting high mobility group box-1 (HMGB1), a key inflammatory mediator. Fifty adult male Wistar rats were randomly allocated into four groups: control, IR, IR + FA pretreatment, and FA alone.

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