Therapeutic peptides of L.: Anti-genotoxic molecules against human hepatocellular carcinoma and hepatitis C virus.

To assist the development of new therapeutic strategies for several disorders, biologically active peptides/proteins obtained from plant sources can be considered. Current study expected to determine the biological activities of peptide fractions of against hepatocellular carcinoma cell lines (HepG2/ADM, HepG2, SMMC-7721, and QGY-7703), as well as normal cell line to prove their selectivity. Moreover, anti-genotoxicity and antiviral activity against the hepatitis C virus (HCV) were assessed.

Coronatine elicitation alters chemical composition and biological properties of cumin seed essential oil.

The present experiment evaluated how coronatine (COR) elicitation affects chemical and biological properties of cumin (Cuminum cyminum L.) seed essential oil (CSEO). Following isolation of the EO, its chemical composition was analyzed by gas chromatography-mass spectrometry; also, its bioactivities in terms of antimicrobial/antifungal, cytotoxic (measured by MTT assay) and antioxidant effects (evaluated by DPPH, β-carotene bleaching (BCB) and TBARS methods) were evaluated.