Publications by authors named "Fatemeh Rahimi Mehdi Abad"
Evaluation of H19, Mest, Meg3, and Peg3 genes affecting growth and metabolism in umbilical cord blood cells of infants born to mothers with gestational diabetes and healthy mothers in Rafsanjan City, Iran.
Fatemeh Rahimi Mehdi Abad Mohammad Reza Hajizadeh Mehdi Mahmoodi Zahra Jalali Fatemeh Nazem Kazeruni Mojgan Noroozi Karimabad
J Dev Orig Health Dis
April 2023
Article Synopsis
- * Researchers compared gene expression (MEG3, PEG3, H19, and MEST) in the cord blood of infants born to mothers with gestational diabetes mellitus (GDM) and those born to healthy mothers.
- * Results showed reduced levels of these genes in infants from GDM mothers, suggesting that epigenetic changes in gene methylation may contribute to these differences, highlighting the need for further research on GDM's effects.
Opioid use accelerates normal aging in adults that raises a question on whether it may trans-generationally affect aging and aging biomarkers in the offspring of users as well? In the present research, we investigated the relative telomere length in umbilical cord blood of newborns born to opioid consuming mothers compared to normal controls. Telomere length shortening is a known biomarker of aging and aging related diseases. Its measure at birth or early in life is considered as a predictor of individual health in adulthood.
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