Publications by authors named "Fatemeh Paknia"

Article Synopsis
  • A rapidly emerging multidrug-resistant fungal pathogen presents a significant global health challenge, with cases reported in over 47 countries and limited treatment options due to increasing antifungal resistance.
  • Conventional detection methods are often ineffective, necessitating innovative approaches to combat infections like cutaneous candidiasis.
  • Nanoparticle-based therapies, incorporating materials such as silver and gold, show promise in treating these infections, with advancements in their mechanisms and applications potentially leading to improved clinical outcomes and lower mortality rates.
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This review article highlights the innovative role of metal-organic frameworks (MOFs) in addressing global healthcare challenges related to microbial infections. MOFs, comprised of metal nodes and organic ligands, offer unique properties that can be applied in the treatment and diagnosis of these infections. Traditional methods, such as antibiotics and conventional diagnostics, face issues such as antibiotic resistance and diagnostic limitations.

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Numerous disorders go untreated owing to a lack of a suitable drug delivery technology or an appropriate therapeutic moiety, particularly when toxicities and side effects are a major concern. Treatment options for microbiological infections are not fulfilled owing to significant adverse effects or extended therapeutic options. Advanced therapy options, such as active targeting, may be preferable to traditional ways of treating infectious diseases.

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