Effects of Xenogen Mesenchymal Stem Cells and Cryo-Platelet Gel on Intractable Wound Healing in Animal Model (Rat).

Background: Today, the effects of growth factors and mesenchymal stem cells (MSCs) in promoting wound healing has been confirmed.

Objective: This study aimed to investigate the effect of MSCs and platelet cryogel on wound healing.

Methods: 40 male wistar rats were randomly divided into five groups (n=8).

Adiponectin modulates synaptic plasticity in hippocampal dentate gyrus.

Recent studies have suggested the involvement of some metabolic hormones in memory formation and synaptic plasticity. Insulin dysfunction is known as an essential process in the pathogenesis of sporadic Alzheimer's disease (AD). In this study we examined whether adiponectin (ADN), as an insulin-sensitizing adipokine, could affect hippocampal synaptic plasticity.