Comparison of mild and microdose GnRH agonist flare protocols on IVF outcome in poor responders.

Purpose: To compare the IVF outcome of clomiphene citrate/gonadotropin/antagonist (mild protocol) and microdose GnRH agonist flare protocols for poor responders undergoing in vitro fertilization.

Methods: 159 poor responder patients were randomized and ovarian stimulation was performed with clomiphene citrate, gonadotropin and antagonist (group I) or microdose GnRH agonist flare (group II) protocols. Main outcome was clinical pregnancy rate and secondary outcomes were doses of gonadotropin administration and duration of stimulation.

Comparison of early pregnancy and neonatal outcomes after frozen and fresh embryo transfer in ART cycles.

Purpose: frozen embryo transfer (FET) has no clear negative impact on neonatal outcome compared with fresh embryo transfer (ET) and appears to result in similar or even better neonatal outcome. The objective of this study was to compare early pregnancy outcome and neonatal health of children born after FET and fresh ET.

Methods: in this study early pregnancy and neonatal outcomes after FET (n = 200) and fresh ET (n = 500) were compared.