Publications by authors named "Fatemeh Hosseini Tabatabaie"
Article Synopsis
- - The COVID-19 pandemic has prompted research into new drugs and treatments that focus on modifying the immune response to control inflammation, particularly through the endocannabinoid system and cannabinoids like Cannabidiol (CBD).
- - High levels of inflammatory cytokines, especially IL-6, are linked to severe complications in COVID-19 patients, and cannabinoids may help reduce these cytokine storms by regulating immune cell activity.
- - While CBD is considered safe and may benefit COVID-19 management, careful consideration of dosing, medication interactions, and side effects is necessary before use in clinical settings.
Epstein-Barr virus-related malignancies have been linked to variations in the sequences of EBV genes, notably EBNA1. Therefore, the purpose of this study was to examine the DBD/DD domain and USP7 binding domain sequences at the C-terminus of the EBNA1 gene in patients with chronic lymphocytic leukemia (CLL). This study included 40 CLL patients and 21 healthy volunteers.
View Article and Find Full Text PDFBackground & Objective: Epstein-Barr virus nuclear antigen-1 (EBNA1) is one of the most important proteins of Epstein-Barr virus (EBV) that might be mutated in various related cancers. The purpose of this study was to compare EBNA1 mutations in the C-terminal region between patients with cervical and ovarian cancer and healthy individuals.
Methods: As test and control groups, 18 EBV-positive paraffin-embedded samples of cervical and ovarian cancer and 10 age- and gender-matched healthy volunteers who did not have cancer but were EBV-positive were both used.
The attachment of SARA-CoV-2 happens between ACE2 and the receptor binding domain (RBD) on the spike protein. Mutations in this domain can affect the binding affinity of the spike protein for ACE2. S477N, one of the most common mutations reported in the recent variants, is located in the RBD.
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