Background: TGF-β1 is known to promote cardiac remodeling and fibrosis during Congestive Heart Failure (CHF). In this study, an attempt was made to investigate expression of Transforming Growth Factor beta1 (TGF-β1) and relative expansion or contraction of regulatory T-cell (Tregs) population in peripheral blood of patients with Chronic Heart Failure (CHF).
Methods: Real-time PCR assay was used to investigate expression and post-stimulation levels of TGF-β1 in cell culture supernatant of Peripheral Blood Mononuclear Cells (PBMC) of 42 patients with CHF and 42 controls.
In the present work, mesoporosity is introduced into highly siliceous HZSM-5 zeolites (SiO/AlO = 400) by a two-step path including desilication using NaAlO and TPAOH (tetrapropylammonium hydroxide) mixtures, followed by acid washing treatment. The physicochemical properties of conventional microporous HZSM-5 and all treated samples were characterized by ICP-OES, XRD, FE-SEM, BET and NH-TPD methods. The catalytic performance of the HZSM-5 samples was determined in methanol to propylene conversion reaction at 460 °C and methanol WHSV of 0.
View Article and Find Full Text PDFAim: To assess the association between the levels of interleukin 17 (IL-17) and T-helper 17 count and symptom severity and etiology of chronic heart failure.
Methods: This single-center prospective case-control study, conducted from December 1, 2015 to January 1, 2017 in Tehran Heart Center, evaluated gene expression of IL-17, relative count of (CD4+IL17+) Th17 cells and CD4+ helper T-cells in peripheral blood mononuclear cells of 42 patients with CHF and 42 matched controls. A multiple regression model assessed the predictors of peripheral IL-17 expression and Th17 count in patients with CHF.