Genetically engineered phages and engineered phage-derived enzymes to destroy biofilms of antibiotics resistance bacteria.

"An impregnable stronghold where one or more warrior clans can evade enemy attacks" may serve as a description of bacterial biofilm on a smaller level than human conflicts. Consider this hypothetical conflict: who would emerge victorious? The occupants of secure trenches or those carrying out relentless assault? Either faction has the potential for triumph; the defenders will prevail if they can fortify the trench with unwavering resolve, while the assailants will succeed if they can devise innovative means to breach the trench. Hence, bacterial biofilms pose a significant challenge and are formidable adversaries for medical professionals, often leading to the failure of antibiotic treatments in numerous hospital infections.

Antibiotic resistance, virulence and genetic diversity of in community- and hospital-acquired urinary tract infections in Iran.

is among the most important causes of urinary tract infection (UTI). The aim of this study was to investigate the prevalence and correlation of antibiotic resistance with virulence characteristics and genetic diversity in isolated from UTIs in Iran. Phenotypic tests and antibiotic susceptibility were carried out on the isolates.