Publications by authors named "Fatemeh Chehregosha"
Introduction: This study aims to determine the effects of fenugreek seed dry extract (FDE) on the glycemic indices, lipid profile, and prooxidant-antioxidant balance (PAB) in patients with type 2 diabetes (T2D).
Methods: A double-blind randomized clinical trial was carried out on 54 individuals with T2D. Participants were randomly assigned to a FDE group (received 3 tablets containing 335 mg of FDE daily for 8 weeks) or a placebo group (received tablets containing microcrystalline cellulose).
Article Synopsis
- Metabolic syndrome (MetS) involves a group of metabolic issues that pose a significant health risk, and fenugreek has shown potential benefits for some of its components.
- A meta-analysis of 29 randomized controlled trials was performed to evaluate fenugreek's impact on various MetS indicators like fasting plasma glucose (FPG), triglycerides (TG), and blood pressure.
- The findings suggest that fenugreek significantly lowers FPG, TG, waist circumference, and systolic blood pressure, while also improving high-density lipoprotein (HDL) levels; however, it did not significantly affect diastolic blood pressure or body mass index (BMI).
Melatonin effectiveness in amelioration of oxidative stress and strengthening of antioxidant defense system: Findings from a systematic review and dose-response meta-analysis of controlled clinical trials.
Clin Nutr ESPEN
April 2022
Background And Aim: Oxidative stress is involved in the development of chronic diseases. It has been suggested that melatonin has a protective role against oxidative stress by activation of antioxidant enzymes and scavenging free-radicals. Present study aimed to investigate the effect of melatonin supplementation on oxidative stress and antioxidant biomarkers such as malondialdehyde (MDA), increased total antioxidant capacity (TAC), superoxide dismutase (SOD), and Glutathione peroxidase (GPx).
View Article and Find Full Text PDF