Evaluation of salivary beta-2 microglobulin as HBV proliferation marker in HBS Ag(+), HBV DNA PCR(+) and HBV DNA PCR(-) subjects.

Aim: The aim of this study was to determine the concentration of salivary B2M as a marker of viral proliferation in HBS Ag(+), HBV DNA PCR(+) and Hbs Ag(+) and HBV DNA PCR(-) subjects.

Background: Beta-2 microglobulin (B2M) is responsible for transmission of viral antigens such as Hepatitis B (HBV) on the surface of liver cells as part of an HLA complex.

Patients And Methods: In this case control study, 25 PCR(+) and 2 PCR(-) patients were included.