Bacteriological Profile and Antibiogram of Blood Stream Infection in a Tertiary Teaching Hospital of Bangladesh.

Blood stream infection (BSI) is of the most devastating infection of any hospital which has a high mortality. Staphylococcus aureus, coagulase-negative staphylococci (CONS) and enterococcus species are commonest isolated bacteria. This was a cross-sectional descriptive study conducted at the Sylhet Women's Medical College Hospital from October 2022 to March 2023.

Phytochemical Profiling and Pharmacological Evaluation of Methanolic Leaf Extract of for Cytotoxic, Anti-inflammatory, Antioxidant, Antiarthritic, and Analgesic Activities.

(Family: Fabaceae) is traditionally used in Ayurvedic medicine for various medicinal purposes, including as a treatment for wounds, leprosy, skin diseases, fever, diabetes, etc. Although the root and stem of this plant have a significant medicinal value, there was little research on the leaves of this plant. This study aimed to investigate the qualitative phytochemical profile and evaluate the in vitro cytotoxic, anti-inflammatory, antioxidant, and antiarthritic activities, as well as the in vivo anti-inflammatory and analgesic activities, of leaf extract.

A case of peripartum cardiomyopathy in dichorionic diamniotic twin pregnancy.

Peripartum cardiomyopathy (PPCM) is an uncommon life-threatening condition that is characterized by heart failure with reduced ejection fraction during late pregnancy or within 5 months of postpartum in the absence of other causes of heart failure. Despite advances in managing PPCM, the pathophysiology of it is still poorly understood. This article reviews the diagnostic challenges and management of PPCM, specifically highlighting a rare presentation of PPCM characterized by oxygen desaturation alone.

Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry.

Incidence and severity of prostate cancer (PrCa) substantially varies across ancestries. American men of African ancestry (AA) are more likely to be diagnosed with and die from PrCa than the those of European ancestry (EA). Published polygenic risk scores for developing prostate cancer, even those based on multi-ancestry genome-wide association studies, do not address population-specific genetic mechanisms underlying PrCa risk in men of African ancestry.

Physico-mechanical characterization and DFT studies of benzoyl peroxide treated water hyacinth reinforced polypropylene composites.

The use of eco-friendly natural fiber-reinforced polymer composites is rapidly expanding across diverse sectors. The rapid spread of water hyacinth disrupts aquatic ecosystems by modifying the pH of water and salinity in Bangladesh. This work investigated on the impact of incorporating both untreated and chemically treated water hyacinth fibers into polypropylene (PP).

Antimicrobial Susceptibility Patterns of Species and Molecular Detection of Isolated from Patients with Urinary Tract Infection in a Tertiary Care Hospital in Bangladesh.

One of the most prevalent infectious diseases identified in both communities and hospitalized patients is urinary tract infection (UTI). is evolved into a clinically pertinent uropathogen due to its evolving resistance to multiple antimicrobial agentsThis study, detects antimicrobial susceptibility patterns of species and molecular detection of from patients with urinary tract infections. In this cross-sectional observational study, 165 urine samples were obtained from clinically diagnosed patients with UTIs of different ages and gender.

Loss Enhances Disease Progression in a Murine Model of Osteosarcoma.

Osteosarcoma is an aggressive bone malignancy, molecularly characterized by acquired genome complexity and frequent loss of and . Obtaining a molecular understanding of the initiating mutations of osteosarcomagenesis has been challenged by the difficulty of parsing between passenger and driver mutations in genes. Here, a forward genetic screen in a genetic mouse model of osteosarcomagenesis initiated by and conditional loss in pre-osteoblasts identified that loss contributes to OS progression.

DNA Quantity and Quality Comparisons between Cryopreserved and FFPE Tumors from Matched Pan-Cancer Samples.

Personalized cancer care requires molecular characterization of neoplasms. While the research community accepts frozen tissues as the gold standard analyte for molecular assays, the source of tissue for testing in clinical cancer care comes almost universally from formalin-fixed, paraffin-embedded tissue (FFPE). As newer technologies emerge for DNA characterization that requires higher molecular weight DNA, it was necessary to compare the quality of DNA in terms of DNA length between FFPE and cryopreserved samples.

Enhancing rice growth and yield with weed endophytic bacteria Alcaligenes faecalis and Metabacillus indicus under reduced chemical fertilization.

Endophytic bacteria, recognized as eco-friendly biofertilizers, have demonstrated the potential to enhance crop growth and yield. While the plant growth-promoting effects of endophytic bacteria have been extensively studied, the impact of weed endophytes remains less explored. In this study, we aimed to isolate endophytic bacteria from native weeds and assess their plant growth-promoting abilities in rice under varying chemical fertilization.

Psychometric Validation of the Translated and Adapted Bengali Version of the HLS-EU-Q16/Q6 for Adults.

Health Literacy (HL) emerges as a critical tool in addressing the escalating burden of noncommunicable diseases (NCDs) and their associated costs. Particularly in Bangladesh, where the inadequacy of HL presents multifaceted challenges, there is an urgent need to address this issue. This study aimed to translate and evaluate the Bengali versions of the European Health Literacy Questionnaire with 16 items (HLS-EU Q16) and its shorter 6-item version (HLS-EU Q6), as there is currently no validated Bengali tool for assessing HL.

DeepChestGNN: A Comprehensive Framework for Enhanced Lung Disease Identification through Advanced Graphical Deep Features.

Lung diseases are the third-leading cause of mortality in the world. Due to compromised lung function, respiratory difficulties, and physiological complications, lung disease brought on by toxic substances, pollution, infections, or smoking results in millions of deaths every year. Chest X-ray images pose a challenge for classification due to their visual similarity, leading to confusion among radiologists.

Predictors of poor neurodevelopmental outcomes in neonates with clinically observed seizures: A prospective observational study in a tertiary care hospital of Bangladesh.

Neonatal seizures can lead to long-term neurodevelopmental problems. This study aims to identify predictors of poor developmental outcomes in neonates with seizures to aid in early intervention and referral for follow-up and rehabilitation. This observational study was conducted in the Department of Neonatology and Institute of Paediatric Neurodisorder and Autism, Bangabandhu Sheikh Mujib Medical University.

Prevalence of and factors associated with zero-dose and under-immunized children in selected areas of Bangladesh: Findings from Lot Quality Assurance Sampling Survey.

Background: In the era of Gavi's 5.0 vision of "leaving no one behind with immunization", childhood routine vaccination in missed communities is considered as a priority concern. Despite having a success story at the national level, low uptake of immunization is still persistent in selected pocket areas of Bangladesh.

Prevalence of Abnormal Semen Parameters among the Infertile Couples Seeking Infertility Treatment.

Infertility, affecting 60 to 80 million couples globally, is clinically defined as the inability to conceive after 12 months of unprotected sexual contact. Male factors contribute significantly, comprising 40.0% to 50.

Characterization of textile effluent treatment plant sludge and its industrial application in fired clay bricks with health risk assessment.

The textile industry in Bangladesh faces environmental and health challenges due to the disposal of solid waste from Effluent Treatment Plants (ETPs). To address this issue, a study was conducted using soil from a brick industry near Dhaka, amending it with varying amounts of dry sludge to create clay bricks. The original soil had a loam texture and medium plasticity.

The Impact of use of Modified WHO Partograph on Labour Progress and Delivery: Outcome among Spontaneous and Induced Labour in Nulliparous Women at Term.

Labour is a normal physiological process considered by a progressive rise in frequency, intensity, and duration of uterine contractions resulting in effacement and dilatation of the cervix with descent of the fetus over the birth canal. Spontaneous or Induced labour has a significant role in the eventual mode of delivery and neonatal outcome. This study aims to compare mean duration of labour and maternofoetal outcome of spontaneous versus induced labour among nulliparous women.

Development of an automated optimal distance feature-based decision system for diagnosing knee osteoarthritis using segmented X-ray images.

Knee Osteoarthritis (KOA) is a leading cause of disability and physical inactivity. It is a degenerative joint disease that affects the cartilage, cushions the bones, and protects them from rubbing against each other during motion. If not treated early, it may lead to knee replacement.

The pectinolytic activity of Burkholderia cepacia and its application in the bioscouring of cotton knit fabric.

Background: Enzymatic catalysis in different industrial applications is often preferred over chemical methods due to various advantages, such as higher specificity, greater efficiency, and less environmental footprint. Pectinases are a group of enzymes that catalyze the degradation of pectic compounds, the key components of plant middle lamella and the primary cell wall. Pectinases have found applications in multiple industrial processes, including cotton bioscouring, fruit juice extraction and its clarification, plant fiber degumming, paper making, plant biomass liquefaction, and saccharification, among others.

Investigations of hemato-biochemical and histopathological parameters, and growth performance of walking catfish (Clarias batrachus) exposed to PET and LDPE microplastics.

Fish inhabiting various trophic levels are affected differently as the presence of microplastic (MP) in the water column and their ingestion by fish varies. Walking catfish (Clarias batrachus) inhabits the bottom of the water bodies. To understand the effects of MP, we exposed C.

Disease-associated metabolic pathways affected by heavy metals and metalloid.

Increased exposure to environmental heavy metals and metalloids and their associated toxicities has become a major threat to human health. Hence, the association of these metals and metalloids with chronic, age-related metabolic disorders has gained much interest. The underlying molecular mechanisms that mediate these effects are often complex and incompletely understood.

A Computer-Aided Diagnostic System to Identify Diabetic Retinopathy, Utilizing a Modified Compact Convolutional Transformer and Low-Resolution Images to Reduce Computation Time.

Diabetic retinopathy (DR) is the foremost cause of blindness in people with diabetes worldwide, and early diagnosis is essential for effective treatment. Unfortunately, the present DR screening method requires the skill of ophthalmologists and is time-consuming. In this study, we present an automated system for DR severity classification employing the fine-tuned Compact Convolutional Transformer (CCT) model to overcome these issues.