Post-vaccination immune thrombocytopenia (ITP) is a rare but recognized adverse event believed to result from an autoimmune reaction triggered by the vaccine. This case report presents the fourth documented instance of severe ITP requiring splenectomy following the administration of a COVID-19 vaccine. The patient, a 54-year-old previously healthy female with no familial history of autoimmune or hematological disorders, developed ITP two weeks after the first dose of the COVID-19 vaccine.
View Article and Find Full Text PDFStomas serve various purposes, and surgical closure of temporary stomas is typically performed once the underlying reason for their creation has been resolved. However, spontaneous closure of a stoma without surgical intervention is exceptionally rare. Here, we present a case of spontaneous stoma closure.
View Article and Find Full Text PDFMammary myofibroblastoma is a rare benign tumor. It is mainly seen in older men and postmenopausal women. These tumors can be presented with a palpable mass or can be discovered incidentally on routine screening.
View Article and Find Full Text PDFOrthognathic surgery can alter the dental, skeletal, soft tissue, and dimensional changes in the oropharyngeal region. Studies have shown a posterior positioning of the hyoid bone and tongue position after mandibular setback surgery, this in turn can have a negative influence on the upper airway space that could lead to breathing problems such as obstructive sleep apnea. Mandibular setback surgery is commonly used for functional and aesthetic correction in mandibular prognathism patients.
View Article and Find Full Text PDFMandible reconstruction is one of the major challenges that face any maxillofacial surgeon worldwide. Different approaches and methods are used for mandible reconstruction, including pedicle flaps, titanium reconstruction plates, and bone grafts. A free fibular flap is used commonly and is considered the gold standard in mandibular reconstruction with a good success rate.
View Article and Find Full Text PDFBackground: Isolated iliac artery aneurysms are rare and difficult to diagnose. It is more common in males. It can be asymptomatic at diagnosis or can present with frank rupture, or symptoms caused by compression on nearby organs.
View Article and Find Full Text PDFBackground: Antibiotic-resistant Acinetobacter baumannii is a continuously-emerging worldwide health crisis, with mortality rates approaching 50% in intensive care unit (ICU) patients. The objective of this study was to evaluate regional, patient-related, and organism-related predictors of survival among critically-ill patients with confirmed Acinetobacter infection.
Methods: This prospective cohort study was conducted within ten ICUs across six geographically- and climatologically-distinct cities across Saudi Arabia over 13 months.
Background: Clival cystic lesions are not frequently seen in neurosurgery. Cystic lesion in the clivus can be part of a neoplastic process such as chordoma, chondrosarcoma, plasmacytoma, or metastasis. Rare types of pure cystic clival lesions include simple bone cysts and arachnoid cysts, which are asymptomatic most of the time and do not cause symptoms until they reach a large size.
View Article and Find Full Text PDFWe report the use of intravenous Methylene blue to treat the hypotension occurring following adrenal vein ligation in a case of pheochromocytoma resection in a child. The potential benefits and problems, including correct dosage, are discussed.
View Article and Find Full Text PDFTo assess the development of the fetal stomach, we performed 162 esophageal injections of contrast media into spontaneously aborted normal fetuses from 7.5 to 26 weeks of gestation. The length of esophagus and trunk, greater and lesser curvature, and vertical and oblique axis of stomach were measured, and the means and standard deviations at each gestational age were calculated.
View Article and Find Full Text PDFThe camel has a typically elongated mammalian tongue, which tapers to a dorsally flattened tip. The filiform papillae are mostly of the simple type which are scattered over the dorsum and the lateral edges of the tongue. The fungiform papillae are scattered among the filiform papillae.
View Article and Find Full Text PDFFunct Dev Morphol
April 1992
A quantitative morphometric study, using a routine histological technique, was carried out with 72 rats aged 7 and 15 days, 1, 4 and 9 months and 1 1/2 years. A micrometric eyepiece, calibrated by means of a stage micrometer, was employed for measurement. Change due to aging included loss of septa, increased fatty infiltration, diminished demarcation of the cortex from the medulla and a decrease in the number of Hassall's corpuscles.
View Article and Find Full Text PDFThe neurotoxicity of single and divided low-dose methotrexate (MTX) and the rescue effect of leucovorin (folic acid) were investigated by light and electron microscopic examination of the cerebellum of Guinea pigs. One group of animals received a single weekly intraperitoneal MTX in a dose of 10 mg/kg, a second received a similar dose divided into three equal fractions, and the third group received MTX rescued with an equal dose of leucovorin. The results showed degeneration of Purkinje cells indicated by shrinkage and distortion of perikarya, dissolution of mitochondrial cristae, and nuclear and nucleolar changes in all groups which received MTX.
View Article and Find Full Text PDFCholinergic innervation of the cornea and iris of the newborn and adult guinea pig was studied by the technique of Karnovsky and Roots (1964). The given structures are both richly innervated. The cholinesterase reaction of the cornea is more strongly positive in adult animals, whereas the intensity of the reaction of the iris in newborn and adult guinea pigs is almost identical.
View Article and Find Full Text PDFPathological changes in the diameters of the lumbar spinal canal may be associated with low back pain. The assessment of the size of the canal is therefore an important diagnostic procedure. Evidence suggests that there are ethnic differences in the dimensions of the canal.
View Article and Find Full Text PDFIn this study 13- to 14-day fetal thymic lobes were implanted within the anterior eye chambers in mice either with or without a syngeneic newborn sympathetic ganglion. It was observed after 6 weeks of implantation that the thymic lobes that grew with the ganglia had fewer lymphoid cells than their counterparts which were grown without the ganglia. The cells that developed within the thymic lobes were Thy-1- and peanut agglutinin-positive.
View Article and Find Full Text PDFThirty-three cases of 1,500 spontaneously-aborted foetuses showed hepatic calcifications. The exact location of these calcifications were confirmed by contrast studies, anatomic dissection, and further histology when necessary. Of them, 18 were calcified hepatic vein thrombi (CHVT), 12 were calcified portal vein thrombi (CPVT), 2 were parenchymal calcifications, and one was mixed.
View Article and Find Full Text PDFThe authors describe a new technique "necrogram" for post-mortem fetal investigations that uses ionic contrast media and employs the principles of diffusion and osmosis for clearing the fetus from contrast injection. It was possible to perform subsequent contrast examinations without the problem of overlapping structures. The study was conducted on 1,500 fetuses with more than 12,000 contrast examinations performed, followed by autopsy.
View Article and Find Full Text PDFActa Anat (Basel)
February 1990
The adrenergic innervation of the urinary bladder of normal female and pregnant rats has been studied using a fluorescence histochemical method. The bladder is richly innervated by adrenergic nerve fibres as is evidenced by the presence of numerous adrenergic nerves in the adventitia, musculosa and submucosa. However, adrenergic nerve cells could not be observed.
View Article and Find Full Text PDFThe dorsum of the camel tongue shows filiform, fungiform, circumvallate and special (wart-like) papillae. Filiform papillae are conical in shape and show different heights and thicknesses at various levels. Fungiform papillae are rounded and are surrounded by robust filiform papillae.
View Article and Find Full Text PDFThe lumbosacral spines of two fetal and twelve adult cadavers have been studied by dissection. Evidence shows that the fifth lumbar intervertebral foramen is crossed on its external aspect by a strong, cord-like corporotransverse ligament passing obliquely downwards, forwards and medially from the inferior aspect of the accessory process of the fifth lumbar vertebra to the lateral surface of the intervertebral disc and the adjacent parts of the bodies of the fifth and first sacral vertebrae. Superficially, the ligament is related to another flat band--the lumbosacral hood.
View Article and Find Full Text PDFLumbar intervertebral foramina have been studied by dissection of fetal and adult cadaveric spines. The results show that these foramina are crossed by ligaments which subdivide the opening into smaller compartments for the structures traversing it. At L1-L4, there appears to be a basic pattern of arrangement of the ligaments.
View Article and Find Full Text PDFActa Anat (Basel)
April 1988
In the present investigation partial degeneration of adrenergic and cholinergic nerves of the heart of guinea pigs following methotrexate treatment has been reported. No appreciable change was observed in the autonomic nerve fibres after 3 days of treatment. However, after prolonged treatment some nerve fibres showed signs of degeneration and a few adrenergic and cholinergic nerve fibres had disappeared.
View Article and Find Full Text PDFThis study was carried out to determine whether the thymic rudiments implanted into the anterior eye chambers of syngenic hosts receive cholinergic neuronal input from the host, similar to the adrenergic neuronal input into the implants, observed in previous studies. In addition, the study was also aimed at examining the effect of this (cholinergic) neuronal input on thymic lymphopoiesis. 13/14-day-old fetal thymic rudiments were implanted into the anterior eye chambers of syngenic (BALB/c) mice.
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